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[氨茶碱对实验性脑出血清醒猫脑血液供应及功能活动的影响]

[Effect of euphylline on the blood supply and functional activity of the brain in waking cats with experimental intracerebral hemorrhage].

作者信息

Saratikov A S, Plotnikov M B, Plotnikova T M

出版信息

Farmakol Toksikol. 1980 Sep-Oct;43(5):566-9.

PMID:7449986
Abstract

Experiments on 26 conscious cats with experimental intrarebral hemorrhage showed that 24-48 hours after blood administration, intracarotid infusion of euphylline promoted EEG returning to normal, enhanced the local blood flow of the test structures of both hemispheres and produced hurried breathing without material changes in the systemic arterial blood pressure. Administration of the drugs in the later periods (days 7-8) was not effective and even produced a decrease in blood supply to the affected hemisphere. EEG tendency towards normal remains unchanged.

摘要

对26只患有实验性脑内出血的清醒猫进行的实验表明,输血后24 - 48小时,经颈动脉注入氨茶碱可促进脑电图恢复正常,增强双侧半球测试结构的局部血流量,并引起呼吸急促,而全身动脉血压无实质性变化。在后期(第7 - 8天)给药无效,甚至会导致患侧半球血液供应减少。脑电图趋向正常的趋势保持不变。

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1
[Effect of euphylline on the blood supply and functional activity of the brain in waking cats with experimental intracerebral hemorrhage].[氨茶碱对实验性脑出血清醒猫脑血液供应及功能活动的影响]
Farmakol Toksikol. 1980 Sep-Oct;43(5):566-9.
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