Larson H E, Price A B
Lancet. 1977;2(8052-8053):1312-4. doi: 10.1016/s0140-6736(77)90363-4.
A toxin was found in the faeces of nine out of nine patients with pseudomembranous colitis and two out of two with antibiotic-associated non-specific colitis. The toxin was neutralised by Clostridium sordellii antitoxin but not by a commercial mixture of C. welchii, oedematiens, and septicum antitoxins. The in-vitro and in-vivo properties of pseudomembranous-colitis toxin closely resemble those of the toxin of C. sordellii.
在9例伪膜性结肠炎患者的粪便中均发现了毒素，在2例抗生素相关性非特异性结肠炎患者的粪便中也发现了毒素。该毒素可被索氏梭菌抗毒素中和，但不能被产气荚膜梭菌、水肿杆菌和败血梭菌抗毒素的商业混合物中和。伪膜性结肠炎毒素的体外和体内特性与索氏梭菌毒素的特性极为相似。
