功能性消化不良患者的消化不良症状与固体食物胃排空。幽门螺杆菌感染的作用。
Dyspeptic symptoms and gastric emptying of solids in patients with functional dyspepsia. Role of Helicobacter pylori infection.
作者信息
Caballero-Plasencia A M, Muros-Navarro M C, Martín-Ruiz J L, Valenzuela-Barranco M, de los Reyes-García M C, Casado-Caballero F J, Rodríguez-Téllez M, López-Mañas J G
机构信息
Dept. of Medicine, School of Medicine, University of Granada, Spain.
出版信息
Scand J Gastroenterol. 1995 Aug;30(8):745-51. doi: 10.3109/00365529509096322.
BACKGROUND
Our aim was to investigate the relation between dyspeptic symptoms, gastric emptying of digestible and indigestible solids, and Helicobacter pylori infection in patients with functional dyspepsia.
METHODS
We used isotopic labeling and radiologic techniques to study gastric emptying of a solid meal and of 10 radiopaque indigestible solids in 50 healthy volunteers and 50 patients with functional dyspepsia. In addition, we determined the presence of seven symptoms of dyspepsia and added the score for each symptom to obtain an index of dyspepsia for each patient.
RESULTS
Seventy-eight per cent of our dyspeptic patients had gastroparesis to a solid meal, and 68% to indigestible solids. We found no apparent relation between gastroparesis or H. pylori infection and dyspeptic symptoms separately or as an index of dyspepsia. Moreover, the presence of the bacteria was not related to gastroparesis to a solid meal or to indigestible solids.
CONCLUSIONS
We conclude that neither symptoms of dyspepsia nor H. pylori appears to be related to gastroparesis to solids. H. pylori infection is not related to dyspeptic symptoms.
背景
我们的目的是研究功能性消化不良患者的消化不良症状、可消化和不可消化固体的胃排空与幽门螺杆菌感染之间的关系。
方法
我们使用同位素标记和放射学技术，研究了50名健康志愿者和50名功能性消化不良患者固体餐以及10种不透X线的不可消化固体的胃排空情况。此外，我们确定了7种消化不良症状的存在情况，并将每种症状的评分相加，得出每位患者的消化不良指数。
结果
我们的消化不良患者中，78%的人固体餐胃排空延迟，68%的人不可消化固体胃排空延迟。我们发现胃排空延迟或幽门螺杆菌感染与消化不良症状单独或作为消化不良指数之间均无明显关系。此外，细菌的存在与固体餐或不可消化固体的胃排空延迟无关。
结论
我们得出结论，消化不良症状和幽门螺杆菌似乎均与固体胃排空延迟无关。幽门螺杆菌感染与消化不良症状无关。
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