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羔羊A组轮状病毒的血清学和基因组特征分析

Serological and genomic characterisation of group A rotaviruses from lambs.

作者信息

Fitzgerald T A, Munoz M, Wood A R, Snodgrass D R

机构信息

Moredun Research Institute, Edinburgh, Scotland.

出版信息

Arch Virol. 1995;140(9):1541-8. doi: 10.1007/BF01322528.

DOI:10.1007/BF01322528
PMID:7487486
Abstract

Four lamb rotaviruses were characterised serologically by reactions with monoclonal antibodies and genomically by hybridisation assays and sequencing. Each was found to be distinct. Three viruses belonged to the bovine genogroup and were of subgroup I. These viruses possessed serotypes G3, G6, and G10. Their corresponding P types were P1, P11, and P14 respectively. The only previous isolation of a rotavirus with VP4 of type P14 was also from lambs. The fourth isolate was G9P8, which is the first record of a G9 rotavirus from a species other than man.

摘要

通过与单克隆抗体的反应对4株羔羊轮状病毒进行血清学鉴定,并通过杂交试验和测序进行基因组特征分析。发现每株病毒都各不相同。3株病毒属于牛基因组群,为I亚群。这些病毒具有G3、G6和G10血清型。它们相应的P型分别为P1、P11和P14。之前唯一一次分离到的具有P14型VP4的轮状病毒也来自羔羊。第四株分离株为G9P8,这是除人以外的其他物种中首次记录到G9轮状病毒。

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