Kawamori T, Tanaka T, Kawase Y, Shiroko J, Tanahashi S, Mori H
First Department of Pathology, Gifu University School of Medicine, Japan.
Clin Investig. 1994 May;72(5):377-80. doi: 10.1007/BF00252831.
An autopsy case of an 83-year-old Japanese woman with pancreatic cancer with significantly elevated serum alpha-fetoprotein levels is reported. The pancreatic tumor was a mucinous cystadenocarcinoma with multiple metastasis to the liver. The immunohistochemistry for alpha-fetoprotein revealed positive reactivity in the cytoplasm of cancer cells in the primary and liver metastatic lesions. The current case is the first reported in which mucinous cystadenocarcinoma of the pancreas produced alpha-fetoprotein.
报告了一例83岁日本女性胰腺癌患者尸检病例，其血清甲胎蛋白水平显著升高。胰腺肿瘤为黏液性囊腺癌，伴有肝脏多发转移。甲胎蛋白免疫组化显示，原发灶及肝脏转移灶癌细胞胞质呈阳性反应。本病例是首例报道的胰腺黏液性囊腺癌产生甲胎蛋白的病例。
