Saalmüller A, Aasted B, Canals A, Dominguez J, Goldman T, Lunney J K, Pauly T, Pescovitz M D, Pospisil R, Salmon H
Federal Research Centre for Virus Diseases of Animals, Tübingen, Germany.
Vet Immunol Immunopathol. 1994 Oct;43(1-3):255-8. doi: 10.1016/0165-2427(94)90145-7.
Among 54 mAb determined to be reactive with porcine T lymphocytes and/or activation antigens, eight mAb (workshop Nos. 005, 031, 080, 091, 092, 093, 094 and 110) derived from different laboratories grouped together in the T11 cluster and were ordered into the SWC1. One mAb (No. 111) which belong also to this group was lost during the workshop. The SWC1 antigen is a molecule expressed on the majority of leukocytes, resting T lymphocytes, monocytes and granulocytes, but not on B lymphocytes. On T lymphocytes it is down-regulated after activation. The molecular mass of the antigen is unknown. Epitope analyses revealed that seven out of the nine mAb recognized similar epitopes on the SWC1 molecule.
在确定与猪T淋巴细胞和/或活化抗原反应的54种单克隆抗体中，来自不同实验室的8种单克隆抗体（研讨会编号005、031、080、091、092、093、094和110）聚集在T11簇中，并被归入SWC1。同属该组的一种单克隆抗体（编号111）在研讨会期间丢失。SWC1抗原是一种在大多数白细胞、静息T淋巴细胞、单核细胞和粒细胞上表达，但不在B淋巴细胞上表达的分子。在T淋巴细胞上，它在活化后下调。该抗原的分子量未知。表位分析显示，9种单克隆抗体中有7种识别SWC1分子上的相似表位。
