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丙型肝炎病毒感染母亲所生母乳喂养婴儿未发生感染。

Absence of infection in breast-fed infants born to hepatitis C virus-infected mothers.

作者信息

Lin H H, Kao J H, Hsu H Y, Ni Y H, Chang M H, Huang S C, Hwang L H, Chen P J, Chen D S

机构信息

Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Republic of China.

出版信息

J Pediatr. 1995 Apr;126(4):589-91. doi: 10.1016/s0022-3476(95)70356-x.

DOI:10.1016/s0022-3476(95)70356-x
PMID:7535353
Abstract

The role of breast-feeding in perinatal transmission of hepatitis C virus (HCV) was explored in 15 HCV-infected mothers and their infants. The 15 carrier mothers had anti-HCV titers ranging from 1:80 to 1:40,000 and also had HCV-ribonucleic acid with concentrations ranging from 10(4) to 2.5 x 10(8) copies/ml. Both anti-HCV antibody and HCV-ribonucleic acid were present in colostral samples in much lower levels, but none of the 11 breast-fed infants had evidence of HCV infection for up to 1 year of age. Thus breast-feeding seems safe for these infants.

摘要

在15名丙型肝炎病毒(HCV)感染的母亲及其婴儿中,探讨了母乳喂养在围产期丙型肝炎病毒传播中的作用。这15名携带病毒的母亲抗-HCV滴度范围为1:80至1:40,000,且丙型肝炎病毒核糖核酸浓度范围为10⁴至2.5×10⁸拷贝/毫升。初乳样本中抗-HCV抗体和丙型肝炎病毒核糖核酸的水平要低得多,但11名母乳喂养的婴儿在1岁之前均无丙型肝炎病毒感染的迹象。因此,母乳喂养对这些婴儿似乎是安全的。

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