接种减毒活土拉弗朗西斯菌的人体血清中白细胞介素6和肿瘤坏死因子的水平。
Levels of interleukin 6 and tumor necrosis factor in serum from humans vaccinated with live, attenuated Francisella tularensis.
作者信息
Krakauer T
机构信息
Applied Research Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland 21702, USA.
出版信息
Clin Diagn Lab Immunol. 1995 Jul;2(4):487-8. doi: 10.1128/cdli.2.4.487-488.1995.
Abstract
The levels of interleukin 6 (IL-6) and tumor necrosis factor alpha in serum did not change significantly during the course of immunization with the live vaccine strain of Francisella tularensis. Higher levels of circulating IL-6 were found in the sera of vaccinees with good antibody responses than in the sera from nonresponders. Preimmunization levels of IL-6 in serum were also higher in responders than in nonresponders.
摘要
在用土拉弗朗西斯菌活疫苗株免疫过程中，血清中白细胞介素6（IL-6）和肿瘤坏死因子α的水平没有显著变化。抗体反应良好的疫苗接种者血清中循环IL-6水平高于无反应者血清中的水平。反应者血清中IL-6的免疫前水平也高于无反应者。
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本文引用的文献
1
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J Leukoc Biol. 1994 Oct;56(4):458-63. doi: 10.1002/jlb.56.4.458.
2
A sensitive, specific immunobioassay for quantitation of human interleukin 6.一种用于定量检测人白细胞介素6的灵敏、特异的免疫生物测定法。
J Immunoassay. 1993 Dec;14(4):267-77. doi: 10.1080/15321819308019854.
3
Cell-mediated and humoral immunity induced by a live Francisella tularensis vaccine.由活的土拉弗朗西斯菌疫苗诱导的细胞介导免疫和体液免疫。
Infect Immun. 1982 Jun;36(3):983-9. doi: 10.1128/iai.36.3.983-989.1982.
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10
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