将洗涤剂相互之间以及与防腐剂作为皮肤“除菌”剂进行比较。
Detergents compared with each other and with antiseptics as skin 'degerming' agents.
作者信息
Lilly H A, Lowbury E J, Wilkins M D
出版信息
J Hyg (Lond). 1979 Feb;82(1):89-93. doi: 10.1017/s002217240002550x.
Three detergent preparations (bar soap, 'Hibiscrub' base and 'LIC 76'), TWO ANTISEPTic preparations (0.5% chlorhexidine in 95% ethyl alcohol and an alcohol jelly, 'Alcogel'), and one antiseptic-detergent solution (4% chlorhexidine gluconate in a detergent base, 'Hibiscrub') were compared for their effectiveness, on a single use, in reducing the yield of bacteria from the hands of volunteers. The antiseptic and antiseptic--detergent preparations were more effective than the detergents, with a mean reduction in yield of skin bacteria of 96.0% after use of alcoholic chlorhexidine and of 81.2% after use of Hibiscrub. One of the detergents, LIC 76, appeared more effective than the others, causing a mean reduction in the yield of skin bacteria of 41.5%, compared with reductions of 4.6% by the Hibiscrub detergent base and an increase of 3.2% with bar soap; unlike the other detergents, LIC 76 was found to have appreciable bacteristatic and bactericidal properties.
比较了三种洗涤剂制剂（香皂、“洗必泰擦洗剂”基质和“LIC 76”）、两种防腐剂制剂（95%乙醇中的0.5%洗必泰以及一种酒精凝胶“Alcogel”）和一种防腐洗涤剂溶液（洗涤剂基质中4%的葡萄糖酸洗必泰“洗必泰擦洗剂”）单次使用时在降低志愿者手部细菌数量方面的效果。防腐剂制剂和防腐洗涤剂制剂比洗涤剂更有效，使用酒精洗必泰后皮肤细菌数量平均减少96.0%，使用洗必泰擦洗剂后减少81.2%。其中一种洗涤剂“LIC 76”似乎比其他洗涤剂更有效，使皮肤细菌数量平均减少41.5%，相比之下，洗必泰擦洗剂基质使细菌数量减少4.6%，香皂使细菌数量增加3.2%；与其他洗涤剂不同，发现“LIC 76”具有明显的抑菌和杀菌特性。
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