Mladenović I, Mićić S, Genbaćev O, Papić N
Institute for the Application of Nuclear Energy-INEP, Belgrade, Yugoslavia.
Arch Androl. 1995 May-Jun;34(3):163-9. doi: 10.3109/01485019508987845.
This study evaluates the clinical usefulness of one additional parameter for assessment of human sperm cell function in vitro--the hypoosmotic swelling test. The hypoosmotic swelling test evaluated the functional integrity of the sperm plasma membrane. The investigation included a comparison of the hypoosmotic swelling test in samples containing motile and immotile spermatozoa and their correlation with the intrauterine insemination outcome. Motile spermatozoa expressed better membrane characteristics, without any importance of the hypoosmotic conditions. Positive correlation exists between HOS results and the outcome of IUI. This test can be a useful addition to the standard battery of semen analyzing tests.
本研究评估了一项用于体外评估人类精子细胞功能的额外参数——低渗肿胀试验的临床实用性。低渗肿胀试验评估精子质膜的功能完整性。该研究包括对含有活动精子和不活动精子的样本进行低渗肿胀试验的比较，以及它们与宫腔内人工授精结果的相关性。活动精子表现出更好的膜特性，低渗条件对此并无影响。低渗肿胀试验结果与宫腔内人工授精的结果呈正相关。该试验可作为精液分析标准检测项目的有益补充。
