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[巴戟天根中的抗抑郁活性成分]

[Antidepressant active constituents in the roots of Morinda officinalis How].

作者信息

Cui C, Yang M, Yao Z, Cao B, Luo Z, Xu Y, Chen Y

机构信息

Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing.

出版信息

Zhongguo Zhong Yao Za Zhi. 1995 Jan;20(1):36-9, 62-3.

PMID:7626209
Abstract

Five compounds having antidepressant activities have been isolated from the roots of Morinda officinalis, a Chinese traditional Yang-tonic drug. These compounds were identified as succinic acid (1), nystose (2), 1F-fructofuranosylnystose (3), inulin-type hexasaccharide (4) and heptasaccharide (5) by chemical and spectroscopic methods. All of the compounds are isolated from the species of genus Morinda for the first time.

摘要

从传统的中国壮阳药巴戟天的根中分离出了五种具有抗抑郁活性的化合物。通过化学和光谱方法,这些化合物被鉴定为琥珀酸(1)、蔗果三糖(2)、1F-呋喃果糖基蔗果三糖(3)、菊粉型六糖(4)和七糖(5)。所有这些化合物均为首次从巴戟天属植物中分离得到。

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Phenotypic, chemical component and molecular assessment of genetic diversity and population structure of Morinda officinalis germplasm.
药用巴戟天种质遗传多样性和群体结构的表型、化学组分和分子评估。
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oligosaccharides increase serotonin in the brain and ameliorate depression promoting 5-hydroxytryptophan production in the gut microbiota.低聚糖可增加大脑中的血清素,并通过促进肠道微生物群中5-羟色氨酸的产生来改善抑郁症。
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Translational Informatics for Natural Products as Antidepressant Agents.天然产物作为抗抑郁剂的转化信息学
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Effects of the Salt-Processing Method on the Pharmacokinetics and Tissue Distribution of Orally Administered How. Extract.盐制方法对口服厚朴提取物药代动力学及组织分布的影响
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