Ozben T, Nacitarhan S, Tuncer N
Department of Biochemistry, Faculty of Medicine, Akdeniz University, Antalya, Turkey.
Ann Clin Biochem. 1995 May;32 ( Pt 3):303-6. doi: 10.1177/000456329503200307.
Urinary excretions of albumin, glycosaminoglycans (GAGS), total sialic acid (TSA), and lipid associated sialic acid (LASA) were measured in 78 non-insulin dependent diabetic patients (NIDDM) and 28 healthy subjects. TSA excretion was significantly higher in normoalbuminuric and microalbuminuric diabetic subjects than the control subjects and TSA excretion was correlated with urinary albumin excretion rate (AER). In normoalbuminuric diabetics, the duration of diabetes correlated significantly with both sialicaciduria and albuminuria. Although serum TSA levels were significantly higher in both diabetic groups than the control subjects, there was no correlation between serum and urinary TSA levels.
在78例非胰岛素依赖型糖尿病患者（NIDDM）和28名健康受试者中测量了白蛋白、糖胺聚糖（GAGS）、总唾液酸（TSA）和脂质相关唾液酸（LASA）的尿排泄量。正常白蛋白尿和微量白蛋白尿糖尿病受试者的TSA排泄量显著高于对照组，且TSA排泄量与尿白蛋白排泄率（AER）相关。在正常白蛋白尿的糖尿病患者中，糖尿病病程与唾液酸尿和白蛋白尿均显著相关。尽管两个糖尿病组的血清TSA水平均显著高于对照组，但血清和尿TSA水平之间无相关性。
