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核造船厂工人辐射诱发的染色体畸变

Radiation-induced chromosome aberrations in nuclear-dockyard workers.

作者信息

Evans H J, Buckton K E, Hamilton G E, Carothers A

出版信息

Nature. 1979 Feb 15;277(5697):531-4. doi: 10.1038/277531a0.

Abstract

The incidence of chromosome aberrations in peripheral blood lymphocytes of 197 dockyard workers has been followed over a 10-yr period. These workers were exposed to mixed neutron-gamma radiation during the refuelling of nuclear reactors, but most exposures were below the internationally accepted maximum permissible level of 5 rem per yr. There was a significant increase in chromosome damage with increasing exposure; aberration frequency was a linear function of dose and was unfluenced by age and time of blood sampling after exposure.

摘要

对197名造船厂工人外周血淋巴细胞中的染色体畸变发生率进行了为期10年的跟踪研究。这些工人在核反应堆换料期间受到中子-γ混合辐射,但大多数辐射剂量低于国际公认的每年5雷姆的最大允许水平。随着辐射剂量增加,染色体损伤显著增加;畸变频率是剂量的线性函数,不受年龄和辐射后采血时间的影响。

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