Pannese E, Rigamonti L, Ledda M, Arcidiacono G
Institute of Histology, Embryology and Neurocytology, University of Milan, Italy.
J Anat. 1994 Dec;185 ( Pt 3)(Pt 3):497-502.
The perikarya of spinal ganglion neurons display numerous slender projections. In the present investigation we have studied whether the extent of these projections is uniform over the entire perikaryal surface or whether there is a difference between the regions of the perikaryon in contact with different microenvironments. In spinal ganglia of the rat and the lizard we have analysed about 200 neuronal cell bodies arranged in pairs and have compared the extent of the projections quantitatively in the areas of interneuronal contact with that in the areas of neuron-to-satellite cell contact. In both species we have found that the projections are present over the entire perikaryal surface and that the overall development of the perikaryal projections is significantly greater in those portions of the surface in contact with satellite cells than in the portions in contact with another neuron. On the basis of these observations we conclude that the outgrowth of perikaryal projections is an intrinsic property of the nerve cell body which is manifested over the entire perikaryal surface; there is, however, an extrinsic influence from the microenvironment of the neuron, which may account for the quantitative differences in different domains of the perikaryal surface.
脊神经节神经元的胞体呈现出许多细长的突起。在本研究中，我们探讨了这些突起在整个胞体表面的分布范围是否均匀，或者胞体与不同微环境接触的区域之间是否存在差异。在大鼠和蜥蜴的脊神经节中，我们分析了约200个成对排列的神经元胞体，并定量比较了神经元间接触区域和神经元与卫星细胞接触区域的突起范围。在这两个物种中，我们发现突起遍布整个胞体表面，并且与卫星细胞接触的表面部分的胞体突起总体发育明显大于与另一个神经元接触的部分。基于这些观察结果，我们得出结论，胞体突起的生长是神经细胞体的一种内在特性，在整个胞体表面都有体现；然而，神经元微环境存在外在影响，这可能是胞体表面不同区域数量差异的原因。
