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Study on the primary visual cortex of visually impaired subjects by means of 123I-IMP SPECT and MRI.

作者信息

Ishikawa N, Nishijo K, Satou M, Takeda T, Itai Y

机构信息

Department of Radiological Sciences, Ibaraki Prefectural University of Health Sciences, Japan.

出版信息

Ann Nucl Med. 1995 May;9(2):105-8. doi: 10.1007/BF03164976.

DOI:10.1007/BF03164976
PMID:7662490
Abstract

We conducted a study of rCBF in the primary visual cortex of visually impaired subjects who have not been subjected to external stimulation for a long period, by means of 123I-IMP SPECT and MRI. The four subjects had lost their sight due to brain tumors (n = 2), glaucoma (n = 1) and trauma (n = 1). 123I-IMP SPECT showed no differences between the visually impaired group and a visually sound control group on visual analysis as well as semiquantitative analysis. MRI of the visually impaired subjects showed no organic changes, such as atrophy, in the occipital cortex. In conclusion, visually impaired subjects have no decrease in rCBF and no anatomical changes in the primary visual cortex.

摘要

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本文引用的文献

1
SPECT in patients with cortical visual loss.
J Nucl Med. 1993 Sep;34(9):1447-51.
2
Cerebral infarction within six hours of onset: prediction of completed infarction with technetium-99m-HMPAO SPECT.发病6小时内的脑梗死：用锝-99m-六甲基丙烯胺肟单光子发射计算机断层扫描预测完全性梗死
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3
Technetium-99m-HMPAO SPECT in partial status epilepticus.锝-99m-六甲基丙二胺肟单光子发射计算机断层扫描在部分性癫痫持续状态中的应用
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Functional magnetic resonance imaging of somatosensory stimulation.躯体感觉刺激的功能磁共振成像
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Quantifying local cerebral blood flow by N-isopropyl-p-[123I]iodoamphetamine (IMP) tomography.通过 N-异丙基-p-[123I]碘安非他明（IMP）断层扫描定量局部脑血流量。
J Nucl Med. 1982 Mar;23(3):196-203.
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Stimulus rate dependence of regional cerebral blood flow in human striate cortex, demonstrated by positron emission tomography.正电子发射断层扫描显示人类纹状皮质局部脑血流的刺激率依赖性。
J Neurophysiol. 1984 May;51(5):1109-20. doi: 10.1152/jn.1984.51.5.1109.
7
[Measurement of regional cerebral blood flow using N-isopropyl-p-(I-123)iodoamphetamine; changes caused by auditory stimulation].[使用N-异丙基-p-(I-123)碘安非他明测量局部脑血流量；听觉刺激引起的变化]
Kaku Igaku. 1986 Nov;23(11):1619-24.
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Positron emission tomography study of human brain functional development.人类大脑功能发育的正电子发射断层扫描研究
Ann Neurol. 1987 Oct;22(4):487-97. doi: 10.1002/ana.410220408.
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Visual stimulation increases technetium-99m-HMPAO distribution in human visual cortex.
J Nucl Med. 1991 Feb;32(2):210-5.
10
N-isopropyl-p-[123I]iodoamphetamine SPECT in MELAS syndrome: comparison with CT and MR imaging.N-异丙基-p-[123I]碘安非他明单光子发射计算机断层扫描在线粒体脑肌病伴乳酸血症和卒中样发作综合征中的应用：与计算机断层扫描和磁共振成像的比较
J Comput Assist Tomogr. 1991 Jan-Feb;15(1):77-82. doi: 10.1097/00004728-199101000-00010.