霍乱弧菌O1和O139对抗菌药物的体外敏感性调查。
Survey of in vitro susceptibilities of Vibrio cholerae O1 and O139 to antimicrobial agents.
作者信息
Yamamoto T, Nair G B, Albert M J, Parodi C C, Takeda Y
机构信息
Department of Bacteriology, School of Medicine, Juntendo University, Tokyo, Japan.
出版信息
Antimicrob Agents Chemother. 1995 Jan;39(1):241-4. doi: 10.1128/AAC.39.1.241.
Abstract
Vibrio cholerae O139 (173 strains) and O1 (221 strains) were tested for their in vitro susceptibilities to 39 antimicrobial agents. Both O139 and O1 strains were highly susceptible to azithromycin, cephems, minocycline, penems, and newer fluoroquinolones. O139 strains (94.8%), O1 Indian El Tor strains (97%), and Bangladeshi El Tor strains (50%) were highly resistant to streptomycin, sulfamethoxazole, and trimethoprim and moderately resistant to chloramphenicol and furazolidone, in sharp contrast to O1 Peruvian El Tor and O1 classical strains. Some Bangladeshi El Tor strains (43.3%) showed tetracycline resistance as well.
摘要
对霍乱弧菌O139（173株）和O1（221株）进行了39种抗菌药物的体外敏感性测试。O139和O1菌株对阿奇霉素、头孢菌素、米诺环素、青霉烯类和新型氟喹诺酮类药物高度敏感。O139菌株（94.8%）、O1印度埃尔托菌株（97%）和孟加拉国埃尔托菌株（50%）对链霉素、磺胺甲恶唑和甲氧苄啶高度耐药，对氯霉素和呋喃唑酮中度耐药，这与O1秘鲁埃尔托菌株和O1古典生物型菌株形成鲜明对比。一些孟加拉国埃尔托菌株（43.3%）也表现出四环素耐药性。
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