头孢孟多的体外研究。
In vitro studies of cefamandole.
作者信息
Bodey G P, Weaver S
出版信息
Antimicrob Agents Chemother. 1976 Mar;9(3):452-7. doi: 10.1128/AAC.9.3.452.
Abstract
Cefamandole is a new cephalosporin antibiotic that was tested in vitro against 540 clinical isolates of gram-positive cocci and gram-negative bacilli. A concentration of 0.39 mug/ml inhibited 95% of the isolates of Staphylococcus aureus. A concentration of 6.25 mug/ml inhibited over 90% of the isolates of Proteus mirabilis and Escherichia coli, 69% of the isolates of Klebsiella pneumoniae, and 31% of the isolates of indole-positive Proteus spp. and Enterobacter spp. It was active against most cephalothin-resistant isolates of E. coli but not of K. pneumoniae.
摘要
头孢孟多是一种新型头孢菌素抗生素，对540株革兰氏阳性球菌和革兰氏阴性杆菌临床分离株进行了体外试验。浓度为0.39微克/毫升时可抑制95%的金黄色葡萄球菌分离株。浓度为6.25微克/毫升时可抑制超过90%的奇异变形杆菌和大肠杆菌分离株、69%的肺炎克雷伯菌分离株以及31%的吲哚阳性变形杆菌属和肠杆菌属分离株。它对大多数头孢噻吩耐药的大肠杆菌分离株有活性，但对肺炎克雷伯菌分离株无活性。
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