利用固相免疫电子显微镜技术将美国10起肠胃炎暴发中的诺如病毒样病毒分为六个抗原组。
Use of solid-phase immune electron microscopy for classification of Norwalk-like viruses into six antigenic groups from 10 outbreaks of gastroenteritis in the United States.
作者信息
Lewis D, Ando T, Humphrey C D, Monroe S S, Glass R I
机构信息
Public Health Laboratory Service, Leeds, United Kingdom.
出版信息
J Clin Microbiol. 1995 Feb;33(2):501-4. doi: 10.1128/jcm.33.2.501-504.1995.
Abstract
Norwalk-like viruses observed in fecal specimens from 10 outbreaks of gastroenteritis investigated in the United States between 1987 and 1992 were analyzed by solid-phase immune electron microscopy. Outbreak virus strains were classified into six antigenic groups: the four types (UK1 to UK4) previously defined in the United Kingdom, Norwalk virus, and the Oklahoma agent that was newly defined in this study. The diversity of antigenic types demonstrated in these outbreaks was greater than previously recognized and will serve as a basis for characterization of these strains at the molecular level.
摘要
采用固相免疫电子显微镜分析法，对1987年至1992年间在美国调查的10起肠胃炎暴发事件的粪便样本中发现的诺如病毒样病毒进行了分析。暴发病毒株被分为六个抗原组：先前在英国定义的四种类型（UK1至UK4）、诺如病毒，以及本研究中新定义的俄克拉荷马病原体。这些暴发事件中显示的抗原类型多样性比之前认识到的更大，将作为在分子水平上对这些毒株进行特征描述的基础。
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