Huet J C, Mansion M, Pernollet J C
Département de Physiologie et Biochimie Végétales, INRA Versailles, France.
Phytochemistry. 1993 Nov;34(5):1261-4. doi: 10.1016/0031-9422(91)80012-p.
Elicitins are toxic, signalling proteins secreted by Phytophthora spp. responsible for the incompatible reaction and systemic leaf necroses. We have sequenced the least toxic known elicitin, which is secreted by Phytophthora cactorum and belongs to the alpha-elicitin class. This 98 residue sequence was compared to eight other known elicitins. In addition to the point mutation already observed to correlate with the differences in necrotic activities, we confirmed the existence of amino acid changes in the central region of the molecule, comparable to those already shown in one of the Phytophthora megasperma megasperma elicitins, to be correlated with toxicity.
激发素是疫霉属分泌的有毒信号蛋白，负责不相容反应和系统性叶片坏死。我们已对已知毒性最小的激发素进行了测序，该激发素由恶疫霉分泌，属于α - 激发素类别。将这个98个残基的序列与其他8种已知激发素进行了比较。除了已观察到的与坏死活性差异相关的点突变外，我们还证实了分子中心区域存在氨基酸变化，类似于在大疫霉的一种激发素中已显示的与毒性相关的变化。
