Olsen S F, Hansen H S, Sandström B, Jensen B
Institute of Epidemiology and Social Medicine, University of Arhus, Denmark.
Br J Nutr. 1995 Mar;73(3):387-95. doi: 10.1079/bjn19950041.
It is well established that marine n-3 fatty acids measured in erythrocyte phospholipids of non-pregnant subjects reflect the subjects' intake of these fatty acids. In 135 pregnant women in the 30th week of gestation we compared intake of marine n-3 fatty acids and energy, estimated by a combined dietary self-administered questionnaire and interview, with fatty acids measured in erythrocyte phospholipids. Daily intake (g/d) and nutrient density of marine n-3 fatty acids (mg/MJ) correlated with the n-3 fatty acid: arachidonic acid ratio (FA-ratio) with correlation coefficients of 0.48 and 0.54 respectively. In a linear regression model with three frequency questions about marine sandwiches, marine cooked meals and fish oil as explanatory variables, and the FA-ratio as dependent variable, the multiple correlation coefficient was 0.46. Conclusions from the study were (1) levels of erythrocyte fatty acids in pregnant women may be employed as a qualitative method to rank subjects according to intake of marine n-3 fatty acids; (2) with respect to the power to explain FA-ratio variability, three simple marine food frequency questions were comparable with intake of marine n-3 fatty acids assessed by an elaborate semiquantitative dietary method involving an interview.
众所周知，非孕妇红细胞磷脂中测得的海洋n-3脂肪酸反映了这些脂肪酸的摄入量。在135名妊娠第30周的孕妇中，我们通过联合饮食自我管理问卷和访谈估计的海洋n-3脂肪酸和能量摄入量，与红细胞磷脂中测得的脂肪酸进行了比较。海洋n-3脂肪酸的每日摄入量（克/天）和营养密度（毫克/兆焦耳）与n-3脂肪酸：花生四烯酸比率（FA比率）相关，相关系数分别为0.48和0.54。在一个线性回归模型中，以关于海洋三明治、海洋熟食和鱼油的三个频率问题作为解释变量，以FA比率作为因变量，多重相关系数为0.46。该研究的结论是：（1）孕妇红细胞脂肪酸水平可作为一种定性方法，根据海洋n-3脂肪酸的摄入量对受试者进行排名；（2）就解释FA比率变异性的能力而言，三个简单的海洋食物频率问题与通过涉及访谈的精细半定量饮食方法评估的海洋n-3脂肪酸摄入量相当。
