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儿童纤维肌痛综合征——一项结局研究。

Fibromyalgia syndrome in children--an outcome study.

作者信息

Buskila D, Neumann L, Hershman E, Gedalia A, Press J, Sukenik S

机构信息

Ben-Gurion University and Soroka Medical Center, Beer Sheva, Israel.

出版信息

J Rheumatol. 1995 Mar;22(3):525-8.

PMID:7783074
Abstract

OBJECTIVE

To assess the outcome of fibromyalgia syndrome (FM) in a 30-month followup study of children with FM.

METHODS

In the original study to assess the prevalence of FM in healthy schoolchildren, we found 21 children with FM and an additional 7 fulfilling the point count criterion only (11 of 18). Fifteen of the 21 and all 7 were recruited for a 2nd assessment in our present study. In all children, a count of 18 tender points (TP) was conducted by thumb palpation. Tenderness of 9 of the TP sites as well as 4 control point sites was further assessed using a Chatillon dolorimeter. All children were questioned concerning the presence of widespread pain or aching. Children were considered to have FM if they met the American College of Rheumatology criteria for diagnosis.

RESULTS

After 30 months, 11 of the 15 children with FM (73%) were no longer fibromyalgic. The mean point count of the 15 children significantly decreased from 12.5 to 4.6 (p < 0.001). The mean tenderness threshold of the 9 tender sites increased from 2.4 to 3.4 kg (p < 0.01), and the mean tenderness threshold of the 4 control sites increased from 4.1 to 5.6 kg (p < 0.05). Of the 7 children initially fulfilling the point count criterion only, none had developed FM. Their mean point count decreased from 11.4 to 3.4 (p = 0.001), and their mean tenderness thresholds increased from 2.7 kg to 3.9 kg (p = 0.001) at tender sites and from 4.3 kg to 6.8 kg (p < 0.001) at control sites.

CONCLUSION

We suggest that the outcome of FM in children is more favorable than in adults. More followup studies are needed to clarify the longterm outcomes of FM in children and adults.

摘要

目的

在一项针对纤维肌痛综合征(FM)患儿的30个月随访研究中评估FM的转归情况。

方法

在最初评估健康学童中FM患病率的研究里,我们发现21例FM患儿以及另外7例仅符合点数标准的患儿(18例中的11例)。本研究中,21例中的15例以及所有7例被招募进行第二次评估。对所有儿童用拇指触诊计数18个压痛点(TP)。使用Chatillon压痛计进一步评估其中9个TP部位以及4个对照部位的压痛情况。询问所有儿童是否存在广泛性疼痛或酸痛。若儿童符合美国风湿病学会的诊断标准,则被认为患有FM。

结果

30个月后,15例FM患儿中有11例(73%)不再患有纤维肌痛。这15例儿童的平均点数从12.5显著降至4.6(p<0.001)。9个压痛部位的平均压痛阈值从2.4千克升至3.4千克(p<0.01),4个对照部位的平均压痛阈值从4.1千克升至5.6千克(p<0.05)。最初仅符合点数标准的7例儿童中,无一人发展为FM。他们的平均点数从11.4降至3.4(p = 0.001),压痛部位的平均压痛阈值从2.7千克升至3.9千克(p = 0.001),对照部位的平均压痛阈值从4.3千克升至6.8千克(p<0.001)。

结论

我们认为儿童FM的转归情况比成人更乐观。需要更多的随访研究来阐明儿童和成人FM的长期转归情况。

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