Königsreuther K A, Jonas J B
Department of Ophthalmology, University Eye Hospital, Erlangen, Germany.
Graefes Arch Clin Exp Ophthalmol. 1995 Apr;233(4):200-4. doi: 10.1007/BF00183592.
Diabetes mellitus is a systemic disease affecting multiple tissues throughout the body. This study was performed to evaluate intravitally the diabetic changes of the optic disc.
Color photographs of 115 eyes with varying severity of diabetic retinopathy and of 29 normal eyes were morphometrically examined.
We found that the size and shape of the optic disc, the neuroretinal rim and the parapapillary atrophy did not differ significantly between the diabetic eyes and the normal eyes. These variables were independent of the degree of diabetic retinopathy. There was a tendency toward decreased visibility of the retinal nerve fiber layer and increased optic disc pallor in the diabetic eyes.
The results indicate that the area and form of the optic disc, the neuroretinal rim and parapapillary atrophy are not altered by diabetes mellitus. This is important for the diagnosis of glaucoma in diabetic patients, since glaucoma leads to a decrease of rim area and an enlargement of parapapillary atrophy. The reduced visibility of the retinal nerve fiber layer, the increased optic disc pallor and the unchanged size of the neuroretinal rim and parapapillary atrophy suggest that diabetes mellitus may be associated with nonglaucomatous optic nerve atrophy.
糖尿病是一种影响全身多个组织的系统性疾病。本研究旨在活体评估视盘的糖尿病性改变。
对115只患有不同严重程度糖尿病视网膜病变的眼睛以及29只正常眼睛的彩色照片进行形态测量检查。
我们发现，糖尿病眼和正常眼在视盘大小和形状、神经视网膜边缘以及视乳头周围萎缩方面没有显著差异。这些变量与糖尿病视网膜病变的程度无关。糖尿病眼中视网膜神经纤维层的可见度有降低趋势，视盘苍白程度增加。
结果表明，糖尿病不会改变视盘的面积和形态、神经视网膜边缘以及视乳头周围萎缩。这对于糖尿病患者青光眼的诊断很重要，因为青光眼会导致边缘区域减小和视乳头周围萎缩扩大。视网膜神经纤维层可见度降低、视盘苍白程度增加以及神经视网膜边缘和视乳头周围萎缩大小不变表明，糖尿病可能与非青光眼性视神经萎缩有关。
