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Why is insulin not a risk factor for coronary heart disease?

作者信息

Jarrett R J

出版信息

Diabetologia. 1994 Sep;37(9):945-7. doi: 10.1007/BF00400952.

DOI:10.1007/BF00400952
PMID:7806026
Abstract
摘要

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1
Why is insulin not a risk factor for coronary heart disease?
Diabetologia. 1994 Sep;37(9):945-7. doi: 10.1007/BF00400952.
2
Insulin secretion and insulin sensitivity pattern is different in isolated impaired glucose tolerance and impaired fasting glucose: the risk factor in Impaired Glucose Tolerance for Atherosclerosis and Diabetes study.在孤立性糖耐量受损和空腹血糖受损中，胰岛素分泌及胰岛素敏感性模式有所不同：糖耐量受损对动脉粥样硬化和糖尿病影响的危险因素研究
Diabetes Care. 2003 Mar;26(3):868-74. doi: 10.2337/diacare.26.3.868.
3
Physical activity, metabolic factors, and the incidence of coronary heart disease and type 2 diabetes.体力活动、代谢因素与冠心病和2型糖尿病的发病率
Arch Intern Med. 2000 Jul 24;160(14):2108-16. doi: 10.1001/archinte.160.14.2108.
4
Cigarette smoking, adiposity, non-insulin-dependent diabetes, and coronary heart disease in Japanese-American men.日裔美国男性中的吸烟、肥胖、非胰岛素依赖型糖尿病和冠心病
Am J Med. 1990 Dec;89(6):761-71. doi: 10.1016/0002-9343(90)90219-4.
5
Insulinopenic diabetes in Africa.非洲胰岛素分泌不足型糖尿病
Br Med J. 1973 Mar 31;1(5856):773-8. doi: 10.1136/bmj.1.5856.773.
6
[Insulin sensitivity, insulin secretion, and degree of glucose tolerance in a group of people at risk for type 2 diabetes mellitus: several methodologic considerations].一组2型糖尿病高危人群的胰岛素敏感性、胰岛素分泌及葡萄糖耐量程度：若干方法学考量
Med Clin (Barc). 2001 Sep 29;117(9):357-8.
7
Epidemiology of diabetes mellitus.糖尿病流行病学
N Z Med J. 1974 Oct 9;80(525):291-9.
8
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Boll Soc Ital Biol Sper. 1984 Mar 30;60(3):485-91.
9
Fasting hyperinsulinaemia and 2-h glycaemia predict coronary heart disease in patients with type 2 diabetes.空腹高胰岛素血症和2小时血糖水平可预测2型糖尿病患者的冠心病。
Diabetes Metab. 2016 Feb;42(1):55-61. doi: 10.1016/j.diabet.2015.10.001. Epub 2015 Oct 31.
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Metabolic and adipose risk factors for NIDDM and coronary disease in third-generation Japanese-American men and women with impaired glucose tolerance.糖耐量受损的第三代日裔美国男性和女性中2型糖尿病和冠心病的代谢及脂肪风险因素。
Diabetologia. 1994 May;37(5):524-32. doi: 10.1007/s001250050142.

引用本文的文献

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Insulin and cardiovascular disease: biomarker or association?胰岛素与心血管疾病：生物标志物还是关联？
Diabetologia. 2012 Dec;55(12):3145-51. doi: 10.1007/s00125-012-2729-4. Epub 2012 Sep 28.
2
Serum leptin and its relation to anthropometric measures of obesity in pre-diabetic Saudis.血清瘦素及其与糖尿病前期沙特人群肥胖人体测量指标的关系。
Cardiovasc Diabetol. 2007 Jul 7;6:18. doi: 10.1186/1475-2840-6-18.
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Occlusive vascular diseases in oral contraceptive users. Epidemiology, pathology and mechanisms.口服避孕药使用者的闭塞性血管疾病。流行病学、病理学及发病机制。

本文引用的文献

1
Insulin deficiency rather than hyperinsulinaemia in newly diagnosed type 2 diabetes mellitus.新诊断2型糖尿病中胰岛素缺乏而非高胰岛素血症。
Diabet Med. 1993 May;10(4):305-12. doi: 10.1111/j.1464-5491.1993.tb00070.x.
2
Relationship of proinsulin and insulin to cardiovascular risk factors in nondiabetic subjects.非糖尿病患者中胰岛素原和胰岛素与心血管危险因素的关系。
Diabetes. 1993 Sep;42(9):1297-302. doi: 10.2337/diab.42.9.1297.
3
High plasma insulin level associated with coronary heart disease in the elderly.老年人群中高血浆胰岛素水平与冠心病相关。
Drugs. 2000 Oct;60(4):721-869. doi: 10.2165/00003495-200060040-00003.
4
Benefits and risks of transfer from oral agents to insulin in type 2 diabetes mellitus.2型糖尿病患者从口服药物转换为胰岛素治疗的益处与风险
Drug Saf. 1999 Jul;21(1):7-22. doi: 10.2165/00002018-199921010-00002.
5
Cardiac and skeletal muscle insulin resistance in patients with coronary heart disease. A study with positron emission tomography.冠心病患者的心肌和骨骼肌胰岛素抵抗。一项正电子发射断层扫描研究。
J Clin Invest. 1996 Nov 1;98(9):2094-9. doi: 10.1172/JCI119015.
6
Impaired glucose tolerance and unidentified diabetes.糖耐量受损和未确诊糖尿病
Postgrad Med J. 1996 Feb;72(844):67-71. doi: 10.1136/pgmj.72.844.67.
7
Lack of relationship between muscle sympathetic nerve activity and skeletal muscle vasodilation in response to insulin infusion.胰岛素输注时肌肉交感神经活动与骨骼肌血管舒张之间缺乏关联。
Diabetologia. 1996 Jan;39(1):91-6. doi: 10.1007/BF00400418.
8
The insulin resistance syndrome: the controversy is dead, long live the controversy!胰岛素抵抗综合征：争议已死，争议万岁！
Diabetologia. 1994 Sep;37(9):956-8. doi: 10.1007/BF00400955.
9
Insulin resistance, compensatory hyperinsulinaemia, and coronary heart disease.
Diabetologia. 1994 Sep;37(9):948-52. doi: 10.1007/BF00400953.
10
Insulin deficiency and insulin resistance in the pathogenesis of NIDDM: is a divorce possible?胰岛素缺乏与胰岛素抵抗在非胰岛素依赖型糖尿病发病机制中的作用：二者能否分离？
Diabetologia. 1995 Aug;38(8):992-7. doi: 10.1007/BF00400591.
Am J Epidemiol. 1993 Jun 1;137(11):1190-202. doi: 10.1093/oxfordjournals.aje.a116621.
4
Insulin as a predictor of coronary heart disease: interaction with apolipoprotein E phenotype. A report from the Multiple Risk Factor Intervention Trial.胰岛素作为冠心病的预测指标：与载脂蛋白E表型的相互作用。多重危险因素干预试验的报告。
Ann Epidemiol. 1994 Jan;4(1):40-5. doi: 10.1016/1047-2797(94)90041-8.
5
The Bedford survey: ten year mortality rates in newly diagnosed diabetics, borderline diabetics and normoglycaemic controls and risk indices for coronary heart disease in borderline diabetics.贝德福德调查：新诊断糖尿病患者、边缘性糖尿病患者和血糖正常对照组的十年死亡率以及边缘性糖尿病患者的冠心病风险指数。
Diabetologia. 1982 Feb;22(2):79-84. doi: 10.1007/BF00254833.
6
Multiple regression analysis of risk factors for cardiovascular disease and cancer mortality in Busselton, Western Australia--13-year study.西澳大利亚州巴瑟尔顿心血管疾病和癌症死亡率风险因素的多元回归分析——13年研究
J Chronic Dis. 1983;36(5):371-7. doi: 10.1016/0021-9681(83)90169-8.
7
Coronary heart disease mortality in relation with diabetes, blood glucose and plasma insulin levels. The Paris Prospective Study, ten years later.冠心病死亡率与糖尿病、血糖及血浆胰岛素水平的关系。十年后的巴黎前瞻性研究。
Horm Metab Res Suppl. 1985;15:41-6.
8
Plasma insulin as coronary heart disease risk factor: relationship to other risk factors and predictive value during 9 1/2-year follow-up of the Helsinki Policemen Study population.血浆胰岛素作为冠心病危险因素：与其他危险因素的关系以及在赫尔辛基警察研究人群9年半随访期间的预测价值。
Acta Med Scand Suppl. 1985;701:38-52. doi: 10.1111/j.0954-6820.1985.tb08888.x.
9
Hyperinsulinemia, upper body adiposity, and cardiovascular risk factors in non-diabetics.
Metabolism. 1988 Apr;37(4):338-45. doi: 10.1016/0026-0495(88)90133-3.
10
Banting lecture 1988. Role of insulin resistance in human disease.1988年班廷讲座。胰岛素抵抗在人类疾病中的作用。
Diabetes. 1988 Dec;37(12):1595-607. doi: 10.2337/diab.37.12.1595.