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综合医院中的经皮内镜下胃造口术:适应证、结局的前瞻性评估以及两种造瘘管设计的随机对照比较

Percutaneous endoscopic gastrostomy in a general hospital: prospective evaluation of indications, outcome, and randomised comparison of two tube designs.

作者信息

Panos M Z, Reilly H, Moran A, Reilly T, Wallis P J, Wears R, Chesner I M

机构信息

Department of Gastroenterology, Birmingham Heartlands Hospital.

出版信息

Gut. 1994 Nov;35(11):1551-6. doi: 10.1136/gut.35.11.1551.

Abstract

The indications for percutaneous endoscopic gastrostomy (PEG) and patient outcome, were examined prospectively in the setting of a general hospital. In the course of 26 months, 76 patients underwent PEG (median age 62 years (range 18-99)) and were followed up for 6887 patient days. The median (range) duration of PEG feeding was 93 (3-785) days. The procedure was carried out for neurological indications in 76% of cases (stroke 51%) and 53% of patients were severely malnourished (body mass index < 17 kg/m2) at the time of referral. In 12 (16%) patients swallowing recovered and the PEG was removed after a median (range) of 55 days (20-150). Three (4%) deaths were related to PEG (one oesophageal perforation, one haemorrhage, and one aspiration pneumonia). One patient developed peritonism and ileus, which resolved with conservative treatment. Minor complications included local sepsis 3%, tube blockage 12%, and tube connector leak 5%. During seven days of observation, demands on nursing time for routine care of the PEG were the same as for nasogastric tube feeding, median (range) 21 (4-42) v 16 (4-40) min/day respectively, but in about half the latter cases the tube had to be replaced at least once. Over 15 months, 29 patients were randomised to receive a 1.9 mm inner, 2.9 mm (9F) outer diameter Fresenius and 27 a 3.0 mm inner, 4.0 mm (12F) outer diameter Bower polyurethane tube and were followed for 2920 and 2388 patient days respectively. There was no difference in the insertion time (median (range) 20 (10-45) v 24 (10-45) min respectively) or number of patients with complications (three v eight patients NS), although there were more minor mechanical problems (three v 12, p < 0.01) with the 12F tube. The internal anchoring device of the 12F tube allowed its non-endoscopic removal, a method applicable too 16% of cases. No tubes were removed because of blockage.

摘要

在一家综合医院中,对经皮内镜下胃造口术(PEG)的适应证及患者预后进行了前瞻性研究。在26个月的时间里,76例患者接受了PEG(中位年龄62岁(范围18 - 99岁)),并进行了6887个患者日的随访。PEG喂养的中位(范围)持续时间为93(3 - 785)天。76%的病例该手术是因神经学适应证而进行的(中风占51%),53%的患者在转诊时严重营养不良(体重指数<17kg/m²)。12例(16%)患者吞咽功能恢复,PEG在中位(范围)55天(20 - 150天)后拔除。3例(4%)死亡与PEG相关(1例食管穿孔、1例出血和1例吸入性肺炎)。1例患者出现腹膜炎和肠梗阻,经保守治疗后缓解。轻微并发症包括局部感染3%、导管堵塞12%和导管接头渗漏5%。在7天的观察期内,PEG常规护理所需的护理时间与鼻胃管喂养相同,中位(范围)分别为21(4 - 42)分钟/天和16(4 - 40)分钟/天,但在后一种情况中约一半的病例导管至少需要更换一次。在15个月的时间里,29例患者被随机分配接受内径1.9mm、外径2.9mm(9F)的费森尤斯导管,27例接受内径3.0mm、外径4.0mm(12F)的鲍尔聚氨酯导管,分别随访了2920和2388个患者日。插入时间(中位(范围)分别为20(10 - 45)分钟和24(10 - 45)分钟)或并发症患者数量(3例对8例,无统计学差异)无差异,尽管12F导管有更多轻微机械问题(3例对12例,p<0.01)。12F导管的内部锚固装置允许非内镜下拔除,该方法适用于16%的病例。没有导管因堵塞而拔除。

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