Löser C, Wolters S, Fölsch U R
I. Medical Department, Christian-Albrechts-University of Kiel, Germany.
Dig Dis Sci. 1998 Nov;43(11):2549-57. doi: 10.1023/a:1026615106348.
After PEG placement at the Medical Department of the University Hospital in Kiel, 210 patients (mean age 61.3 years; 137 men, 73 women) were prospectively followed-up for 133+/-181 days. Close-meshed evaluations of the development of nutritional status, long-term outcome, complications, subjective acceptability, patient care after discharge from the hospital, survival, and nutritional long-term problems were performed. The PEG procedure (duration 13.3+/-4.2 min) was carried out for neurological (42%), ear-nose-throat (28%), and internal medical (30%) indications. Procedure-related mortality was 0%, while altogether 3.8% severe and 20.0% mild complications were observed. Body weight decreased by a mean of 11.4+/-1.5 kg in the three months before and increased by 3.5+/-1.7 kg one year after PEG placement with no significant differences between malignant or benign underlying diseases. Individual subjective acceptability was excellent in 83%, sufficient in 15%, and poor in 2% of patients only. One-year survival rate was 34.3%. The various results of the present prospective study demonstrate that long-term enteral feeding via PEG is a safe, effective, easy-to-practice, and highly acceptable method with excellent long-term results and distinct improvement of nutritional status. Individual decisions for PEG placement should be considered much earlier and more frequently in appropriate patients.
在基尔大学医院内科进行经皮内镜下胃造口术（PEG）后，对210例患者（平均年龄61.3岁；男性137例，女性73例）进行了为期133±181天的前瞻性随访。对营养状况的发展、长期预后、并发症、主观可接受性、出院后患者护理、生存率和营养长期问题进行了细致评估。PEG手术（持续时间13.3±4.2分钟）针对神经科（42%）、耳鼻喉科（28%）和内科（30%）适应症进行。手术相关死亡率为0%，共观察到3.8%的严重并发症和20.0%的轻度并发症。PEG放置前三个月体重平均下降11.4±1.5千克，放置后一年体重增加3.5±1.7千克，恶性或良性基础疾病之间无显著差异。仅2%的患者个体主观可接受性差，83%为优，15%为尚可。一年生存率为34.3%。本前瞻性研究的各项结果表明，通过PEG进行长期肠内喂养是一种安全、有效、易于实施且高度可接受的方法，具有出色长期效果并能显著改善营养状况。对于合适的患者，应更早且更频繁地考虑进行PEG放置的个体决策。
