Aymard M
National Influenza Reference Centre, Lyon, France.
Eur J Epidemiol. 1994 Aug;10(4):463-4. doi: 10.1007/BF01719676.
The identification of a pandemic viral strain will be performed by the National Reference Centres. The well established sentinels network collecting respiratory samples is able to work not only during the winter season but also a part from it and to allow the early detection of new variants. It also supplies pertinent clinical and epidemiological data in order to correlate a new strain with authentic pathogenic and epidemiologic potential. Based on the previous pandemics experiences, and on the current circulating Influenza strains in humans and animals, a limited number of H and N antigens could be expected as component of a new pandemic strain. The recent rapid tests for the detection and the isolation of influenza viruses permit the diagnosis of a new strain within a few days or weeks. Rapid exchanges of data, strains and reagents under the WHO authority would help in a rapid prediction of a pandemic risk.
大流行病毒株的鉴定将由国家参考中心进行。完善的收集呼吸道样本的监测哨点网络不仅能够在冬季发挥作用，在其他季节也能运行，并能早期发现新的病毒变种。它还能提供相关的临床和流行病学数据，以便将新毒株与真正的致病和流行潜力关联起来。基于以往的大流行经验，以及目前在人类和动物中传播的流感毒株情况，预计作为新大流行毒株组成部分的H和N抗原数量有限。最近用于检测和分离流感病毒的快速检测方法能够在几天或几周内诊断出新毒株。在世卫组织的授权下快速交换数据、毒株和试剂将有助于快速预测大流行风险。
