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硝基麝香

Nitro musk.

作者信息

Ippen H

出版信息

Int Arch Occup Environ Health. 1994;66(4):283-5. doi: 10.1007/BF00454368.

DOI:10.1007/BF00454368
PMID:7843840
Abstract

The detection of nitro musk compounds in breast milk and in human adipose tissue is mainly due to the use of such substances as perfume in detergents from which they enter the sewage and finally the whole freshwater system. Due to their low degradability and a high biological concentration factor, they enter the food chain without the toxicological investigations to date allowing any certain conclusions on the effect of such accumulation in the human organism or on the effect of accumulation in ecological systems.

摘要

母乳和人体脂肪组织中检测到硝基麝香化合物,主要是因为洗涤剂中使用了此类物质作为香料,它们由此进入污水,最终进入整个淡水系统。由于其降解性低且生物浓缩系数高,它们进入食物链,而迄今为止的毒理学研究无法就此类物质在人体中的积累效应或在生态系统中的积累效应得出任何确切结论。

相似文献

1
Nitro musk.硝基麝香
Int Arch Occup Environ Health. 1994;66(4):283-5. doi: 10.1007/BF00454368.
2
Occurrence of synthetic musk fragrances in marine mammals and sharks from Japanese coastal waters.日本沿海水域海洋哺乳动物和鲨鱼体内合成麝香香料的出现情况。
Environ Sci Technol. 2005 May 15;39(10):3430-4. doi: 10.1021/es050199l.
3
Occurrence of nitro and non-nitro benzenoid musk compounds in human adipose tissue.人体脂肪组织中硝基和非硝基苯系麝香化合物的存在情况。
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4
Simultaneous congener-specific determination of selected organochlorine compounds and nitro musks in human whole blood samples by solid-phase extraction and capillary gas chromatography with electron capture detection.通过固相萃取和带电子捕获检测的毛细管气相色谱法同时对人全血样本中的特定有机氯化合物和硝基麝香进行同系物特异性测定。
J Anal Toxicol. 2005 Mar;29(2):110-7. doi: 10.1093/jat/29.2.110.
5
Environmental risk assessment of musk ketone and musk xylene in The Netherlands in accordance with the EU-TGD.根据欧盟技术指导文件对荷兰境内的酮麝香和二甲苯麝香进行环境风险评估。
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本文引用的文献

1
An unusual profile of musk xylene-induced drug-metabolizing enzymes in rat liver.麝香二甲苯诱导大鼠肝脏药物代谢酶的异常情况
Biochem Pharmacol. 1993 Apr 22;45(8):1659-65. doi: 10.1016/0006-2952(93)90307-i.
2
Induction of cytochrome P450 1A2 by musk analogues and other inducing agents in rat liver.麝香类似物及其他诱导剂对大鼠肝脏细胞色素P450 1A2的诱导作用
Eur J Pharmacol. 1993 Oct 1;248(3):243-50. doi: 10.1016/0926-6917(93)90051-q.
3
Identification of musk xylene and musk ketone in freshwater fish collected from the Tama River, Tokyo.
东京多摩川采集的淡水鱼中二甲苯麝香和酮麝香的鉴定。
Bull Environ Contam Toxicol. 1981 May;26(5):656-62. doi: 10.1007/BF01622152.
4
Synthetic musk residues in biota and water from Tama River and Tokyo Bay (Japan).日本多摩川及东京湾生物群和水中的合成麝香残留物。
Arch Environ Contam Toxicol. 1983 Jan;12(1):83-9. doi: 10.1007/BF01055006.
5
Neurotoxic properties of musk ambrette.葵子麝香的神经毒性特性。
Toxicol Appl Pharmacol. 1984 Sep 30;75(3):571-5. doi: 10.1016/0041-008x(84)90194-7.
6
Identification, occurrence and mutagenicity in Salmonella typhimurium of two synthetic nitroarenes, musk ambrette and musk xylene, in Indian chewing tobacco and betel quid.印度咀嚼烟草和槟榔中两种合成硝基芳烃(葵子麝香和二甲苯麝香)在鼠伤寒沙门氏菌中的鉴定、存在情况及致突变性
Food Chem Toxicol. 1986 Jan;24(1):27-31. doi: 10.1016/0278-6915(86)90260-7.
7
90-day dermal toxicity study and neurotoxicity evaluation of nitromusks in the albino rat.硝麝香对白化大鼠的90天皮肤毒性研究及神经毒性评估。
Food Chem Toxicol. 1990 Jan;28(1):55-61. doi: 10.1016/0278-6915(90)90136-b.
8
Long-term toxicity/carcinogenicity of musk xylol in B6C3F1 mice.二甲苯麝香对B6C3F1小鼠的长期毒性/致癌性
Food Chem Toxicol. 1990 Aug;28(8):581-6. doi: 10.1016/0278-6915(90)90159-k.
9
Distribution, metabolism, and excretion of musk xylene in rats.二甲苯麝香在大鼠体内的分布、代谢及排泄
Arch Toxicol. 1991;65(4):273-82. doi: 10.1007/BF01968961.
10
Isolation and biological evaluation of potential cancer chemopreventive agents from ambrette musk residue.从黄葵麝香残渣中分离潜在癌症化学预防剂并进行生物学评估。
J Pharm Sci. 1992 Sep;81(9):950-3. doi: 10.1002/jps.2600810923.