Safioleas M, Misiakos E, Manti C, Katsikas D, Skalkeas G
Second Department of Propedeutic Surgery, Athens University Medical School, Laiko General Hospital, Greece.
World J Surg. 1994 Nov-Dec;18(6):859-65. doi: 10.1007/BF00299087.
Human echinococcosis is still endemic in some areas of the world, including Mediterranean countries. Because there is no effective medical therapy, surgery remains the principal mode of treatment. A consecutive of 132 patients operated on for liver hydatid disease between January 1977 and February 1993 were analyzed. There were 60 men (45.4%) and 72 women (54.6%) aged 31 to 88 years (mean 56 years). The right lobe of the liver was affected in 68 cases (51.5%), the left lobe in 31 cases (23.5%), and both lobes in 14 cases (10.6%); there were multiple liver cysts in 7 cases (5.3%), concomitant cysts in other parenchymal organs in 4 cases (3.0%), and disseminated intraabdominal hydatid disease in 8 cases (6.1%). Clinical symptomatology consisted of abdominal pain, fever, jaundice, urticaria, and an abdominal mass. Preoperative diagnosis was established using imaging studies: plain abdominal films, ultrasonography, computed tomography, and serologic tests. Three patients (2.3%) underwent simple closure without drainage, 7 patients (5.3%) cyst excision, 4 patients (3.0%) marsupialization, 1 patient (0.8%) left lateral segmentectomy, 15 patients (11.3%) external drainage, 69 patients (52.3%) omentoplasty, and 33 patients (25.0%) combinations of procedures. Postoperative morbidity was low and consisted of hepatic abscess development, wound infection, bowel obstruction, and biliary leaks. Six patients (4.5%) had recurrent disease. One patient died during the postoperative period because of septic complications. Among the surgical techniques we used, excision of the cyst (when feasible) and omentoplasty produced the lowest complication rates and the best clinical results.
人体包虫病在世界上的一些地区,包括地中海国家,仍然是地方病。由于没有有效的药物治疗方法,手术仍然是主要的治疗方式。对1977年1月至1993年2月间连续接受肝包虫病手术的132例患者进行了分析。其中男性60例(45.4%),女性72例(54.6%),年龄31至88岁(平均56岁)。肝右叶受累68例(51.5%),肝左叶受累31例(23.5%),两叶均受累14例(10.6%);多发性肝囊肿7例(5.3%),其他实质器官合并囊肿4例(3.0%),腹腔内播散性包虫病8例(6.1%)。临床症状包括腹痛、发热、黄疸、荨麻疹和腹部肿块。术前诊断采用影像学检查:腹部平片、超声、计算机断层扫描和血清学检查。3例患者(2.3%)未引流单纯缝合,7例患者(5.3%)行囊肿切除术,4例患者(3.0%)行囊壁开窗术,1例患者(0.8%)行左外叶切除术,15例患者(11.3%)行外引流,69例患者(52.3%)行网膜固定术,33例患者(25.0%)采用多种手术联合。术后发病率较低,包括肝脓肿形成、伤口感染、肠梗阻和胆漏。6例患者(4.5%)复发。1例患者术后因败血症并发症死亡。在我们使用的手术技术中,囊肿切除(可行时)和网膜固定术的并发症发生率最低,临床效果最佳。