Johnson D, Ksciuk H, Woelk H, Sauerwein-Giese E, Frauendorf A
Hordt-Institut, Rödermark, Germany.
J Geriatr Psychiatry Neurol. 1994 Oct;7 Suppl 1:S44-6. doi: 10.1177/089198879400700112.
In a randomized double-blind study, the effect of hypericum extract was compared to that of maprotiline in 24 healthy volunteers. The investigations included measurements of resting EEG as well as visual and acoustic evoked potentials. In resting EEGs, both medications revealed oppositely directed changes in the theta frequencies, and mainly similarly directed changes in alpha and beta frequencies. Measurements of evoked potentials in the theta and beta frequencies supported these results. The results indicate improved cognitive functions mainly with the treatment of hypericum extract.
在一项随机双盲研究中，将金丝桃提取物的效果与麦普替林在24名健康志愿者身上的效果进行了比较。研究包括静息脑电图以及视觉和听觉诱发电位的测量。在静息脑电图中，两种药物在θ频率上显示出相反方向的变化，而在α和β频率上主要显示出相同方向的变化。θ和β频率的诱发电位测量结果支持了这些结果。结果表明，主要是金丝桃提取物的治疗改善了认知功能。
