Griffiths A P, Wyatt J, Jack A S, Dixon M F
Department of Histopathology, Neath General Hospital, West Glamorgan.
J Clin Pathol. 1994 Dec;47(12):1123-4. doi: 10.1136/jcp.47.12.1123.
A series of primary gastric lymphomas and adenocarcinomas was reviewed to assess the prevalence of lymphocytic gastritis in these conditions. Lymphocytic gastritis was more prevalent in patients with gastric adenocarcinoma (16 of 130 cases; 12.3%) and primary gastric lymphoma (six of 45 cases; 13.7%) than in unselected patients undergoing endoscopy (0.83-2.5%). This suggests that these two disparate gastric tumours may share an immunological dysfunction or a common pathogenesis, and this is of interest given that Helicobacter pylori is thought to have a role in the evolution of gastric adenocarcinoma and lymphoma.
回顾了一系列原发性胃淋巴瘤和腺癌,以评估这些疾病中淋巴细胞性胃炎的患病率。淋巴细胞性胃炎在胃腺癌患者(130例中的16例;12.3%)和原发性胃淋巴瘤患者(45例中的6例;13.7%)中比在未经过挑选的接受内镜检查的患者(0.83 - 2.5%)中更常见。这表明这两种不同的胃部肿瘤可能存在免疫功能障碍或共同的发病机制,鉴于幽门螺杆菌被认为在胃腺癌和淋巴瘤的发展中起作用,这一点很有意思。