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将汉加努齐乌-戴歇尔（血清病）抗原鉴定为含有N-羟乙酰神经氨酸的神经节苷脂。

Characterization of the Hanganutziu-Deicher (serum-sickness) antigen as gangliosides containing n-glycolylneuraminic acid.

作者信息

Merrick J M, Zadarlik K, Milgrom F

出版信息

Int Arch Allergy Appl Immunol. 1978;57(5):477-80. doi: 10.1159/000232140.

DOI:10.1159/000232140
PMID:78906
Abstract

Gangliosides that possess the same sugar sequence but differing in the type of sialic acid (N-acetyl- or N-glycolylneuraminic acid) were compared for their reactivity with Hanganutziu-Deicher ('serum sickness') antibodies by double-diffusion gel precipitation tests. Only N-glycolylneuraminic acid containing gangliosides formed precipitation lines with Hanganutziu-Deicher antibodies, thus suggesting that Hanganutziu-Deicher antigens are gangliosides that contain N-glycolylneuraminic acid.

摘要

通过双向扩散凝胶沉淀试验，比较了具有相同糖序列但唾液酸类型（N-乙酰神经氨酸或N-羟乙酰神经氨酸）不同的神经节苷脂与汉-德（“血清病”）抗体的反应性。只有含N-羟乙酰神经氨酸的神经节苷脂与汉-德抗体形成沉淀线，因此表明汉-德抗原是含有N-羟乙酰神经氨酸的神经节苷脂。

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Characterization of the Hanganutziu-Deicher (serum-sickness) antigen as gangliosides containing n-glycolylneuraminic acid.将汉加努齐乌-戴歇尔（血清病）抗原鉴定为含有N-羟乙酰神经氨酸的神经节苷脂。
Int Arch Allergy Appl Immunol. 1978;57(5):477-80. doi: 10.1159/000232140.
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