Brown K N, Benedictson J, Swanby S
Antimicrob Agents Chemother. 1976 Oct;10(4):768-9. doi: 10.1128/AAC.10.4.768.
The antimicrobial activity of gentamicin, tobramycin, sisomicin, and netilmicin (Sch 20569) was compared against 150 strains of organisms. Netilmicin was shown to be the least effective against Pseudomonas strains but to have slightly better activity against Staphylococcus aureus and Escherichia coli than the other agents. The effect of calcium and magnesium in enhancing the differences in activity of these aminoglycosides against Pseudomonas strains was also demonstrated.
比较了庆大霉素、妥布霉素、西索米星和奈替米星(Sch 20569)对150株微生物的抗菌活性。结果表明,奈替米星对铜绿假单胞菌菌株的效果最差,但对金黄色葡萄球菌和大肠杆菌的活性略优于其他药物。还证明了钙和镁在增强这些氨基糖苷类药物对铜绿假单胞菌菌株活性差异方面的作用。