奈替米星琼脂稀释法与纸片扩散法药敏结果的相关性
Correlation of netilmicin agar dilution and disk diffusion susceptibilities.
作者信息
Goldmann D A, Syriopoulou G P, Semple A M
出版信息
Antimicrob Agents Chemother. 1977 Aug;12(2):288-9. doi: 10.1128/AAC.12.2.288.
Abstract
A study of 283 isolates of gram-negative bacilli revealed a good correlation (r = -0.74) between disk diffusion zones of inhibition and agar dilution minimal inhibitory concentrations. Regression analysis suggested that strains with zone sizes =/<11 mm should be considered resistant, but 34 of 45 strains resistant by minimal inhibitory concentration (including 27 strains of Pseudomonas aeruginosa) would have been called susceptible using this break point.
摘要
一项对283株革兰氏阴性杆菌的研究表明，纸片扩散法抑菌圈直径与琼脂稀释法最低抑菌浓度之间存在良好的相关性（r = -0.74）。回归分析表明，抑菌圈直径≤11 mm的菌株应被视为耐药，但在45株通过最低抑菌浓度判定为耐药的菌株中（包括27株铜绿假单胞菌），按照此界值有34株会被判定为敏感。
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本文引用的文献
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Am J Clin Pathol. 1966 Apr;45(4):493-6.
2
Biological activity of netilmicin, a broad-spectrum semisynthetic aminoglycoside antibiotic.奈替米星的生物活性，一种广谱半合成氨基糖苷类抗生素。
Antimicrob Agents Chemother. 1976 Nov;10(5):827-36. doi: 10.1128/AAC.10.5.827.
3
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Antimicrob Agents Chemother. 1976 Nov;10(5):864-5. doi: 10.1128/AAC.10.5.864.
4
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