瑞典北部普马拉病毒（肾综合征出血热）血清IgG抗体的流行情况。
Prevalence of serum IgG antibodies to Puumala virus (haemorrhagic fever with renal syndrome) in northern Sweden.
作者信息
Ahlm C, Linderholm M, Juto P, Stegmayr B, Settergren B
机构信息
Department of Infectious Diseases, University of Umeå, Sweden.
出版信息
Epidemiol Infect. 1994 Aug;113(1):129-36. doi: 10.1017/s0950268800051542.
Abstract
A stratified and randomly-selected population sample was identified in 1990 in order to study the seroprevalence of nephropathia epidemica (haemorrhagic fever with renal syndrome) in Northern Sweden. Sera from 1538 subjects (750 men, 788 women), 25-64 years of age, were analysed for the presence of Puumala virus (PUV) specific-IgG by the indirect immunofluorescence antibody test. Specific IgG was detected in sera from 83 subjects (5.4%). Men and women had similar seroprevalence rates. The highest seroprevalences were found in subjects 55 years or older (8.0%) and among farmers and forestry workers (15.9%). The geographic distribution of seropositive individuals was uneven and there were significantly more seropositive persons in rural than in urban areas (P < 0.05).
摘要
1990年，为研究瑞典北部流行性肾病（肾综合征出血热）的血清流行率，确定了一个分层随机抽样的人群样本。对1538名年龄在25至64岁之间的受试者（750名男性，788名女性）的血清进行检测，采用间接免疫荧光抗体试验分析是否存在普马拉病毒（PUV）特异性IgG。在83名受试者（5.4%）的血清中检测到特异性IgG。男性和女性的血清流行率相似。血清流行率最高的是55岁及以上的受试者（8.0%）以及农民和林业工人（15.9%）。血清阳性个体的地理分布不均衡，农村地区血清阳性者明显多于城市地区（P < 0.05）。
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