Gewirtz G, Squires-Wheeler E, Sharif Z, Honer W G
College of Physicians and Surgeons, Columbia University.
Br J Psychiatry. 1994 Jun;164(6):789-95. doi: 10.1192/bjp.164.6.789.
A cohort of 168 psychotic patients underwent computerised tomography (CT) during their first admission. Cortical atrophy was present in 40% of patients. The frequency of atrophy increased with age, but did not differ between patients with schizophrenia, schizoaffective disorder, bipolar disorder or psychotic depression. Other CT findings of note were present in 6.6% of patients, and included four infarctions, three arachnoid cysts, and one each of venous angioma, colloid cyst, cavum vergae and post-traumatic changes. The frequency of CT findings other than atrophy was increased in the psychotic depression group. The findings support the proposal of the onset of psychosis being an indication for CT.
168名精神病患者在首次入院期间接受了计算机断层扫描(CT)。40%的患者存在皮质萎缩。萎缩的发生率随年龄增长而增加,但在精神分裂症、分裂情感性障碍、双相情感障碍或精神病性抑郁症患者之间没有差异。6.6%的患者有其他值得注意的CT表现,包括4处梗死、3个蛛网膜囊肿、1个静脉血管瘤、1个胶样囊肿、1个透明隔腔和1处创伤后改变。除萎缩外的CT表现发生率在精神病性抑郁症组中有所增加。这些发现支持了将精神病发作作为CT检查指征的提议。