来自竹红菌的竹红菌素对人类免疫缺陷病毒具有光毒性。
Hypocrellin, from Hypocrella bambuase, is phototoxic to human immunodeficiency virus.
作者信息
Hudson J B, Zhou J, Chen J, Harris L, Yip L, Towers G H
机构信息
Department of Pathology, University of British Columbia, Vancouver, Canada.
出版信息
Photochem Photobiol. 1994 Sep;60(3):253-5. doi: 10.1111/j.1751-1097.1994.tb05100.x.
Hypocrellin, a photodynamic perylene quinonoid isolated from the Chinese medicinal fungus Hypocrella bambuase, was evaluated for antiviral activity against the human immunodeficiency virus (HIV-1). Hypocrellin was phototoxic to HIV-1, almost as good as the structurally similar plant pigment hypericin, and like hypericin its activity required visible light. In contrast peroxyhypocrellin had little or no effect on the virus.
竹红菌素是从中国药用真菌竹黄中分离得到的一种光动力苝醌类化合物，对其抗人类免疫缺陷病毒（HIV-1）的活性进行了评估。竹红菌素对HIV-1具有光毒性，几乎与结构相似的植物色素金丝桃素一样有效，并且与金丝桃素一样，其活性需要可见光。相比之下，过氧竹红菌素对该病毒几乎没有影响。
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