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心理教育性家庭管理的可交付性。

Deliverability of psychoeducational family management.

作者信息

Wiedemann G, Hahlweg K, Hank G, Feinstein E, Müller U, Dose M

机构信息

Dept. of Psychiatry, University of Tuebingen, Germany.

出版信息

Schizophr Bull. 1994;20(3):547-56. doi: 10.1093/schbul/20.3.547.

Abstract

As part of an open clinical trial currently underway at the Max Planck Institute of Psychiatry in Munich, the feasibility of behavioral family management (Falloon et al. 1984) for schizophrenia in combination with two different neuroleptic medication strategies was investigated. The treatment approaches were psychoeducational family management with a standard dose or with targeted medication. In this article the following questions were addressed: (1) What proportion of the total schizophrenia population admitted as inpatients might be eligible for psychoeducational family treatment (assessment based on n = 411 over a 33-month period)? (2) How representative of this population are the patients who were randomized to the experimental groups? (3) How many patients dropped out of treatment after entering the trial? The results show that about 60 percent (247) of the patients were eligible for a psychoeducational treatment approach. Of these, 34 percent (85) participated in the trial and were randomized to the treatments. Only 4 percent of the relatives but 20 percent of the patients refused to take part in the study. The 85 trial patients did not differ from the total eligible on the numerous socioeconomic and symptom variables assessed. The treatment dropout rate was 11 percent. Those patients who accepted treatment did not differ from those patients who dropped out on socioeconomic or illness variables. The results indicate that early identification of dropouts is not possible at least with the methods used in this study.

摘要

作为慕尼黑马克斯·普朗克精神病学研究所正在进行的一项开放临床试验的一部分,研究了行为家庭管理(法隆等人,1984年)与两种不同抗精神病药物治疗策略相结合用于精神分裂症治疗的可行性。治疗方法为采用标准剂量或靶向用药的心理教育家庭管理。本文探讨了以下问题:(1)在33个月期间收治的全部住院精神分裂症患者中,有多大比例适合接受心理教育家庭治疗(基于411例患者的评估)?(2)随机分配到实验组的患者在该人群中具有多大代表性?(3)有多少患者在进入试验后退出治疗?结果显示,约60%(247例)的患者适合采用心理教育治疗方法。其中,34%(85例)参与了试验并被随机分配接受治疗。只有4%的亲属但20%的患者拒绝参与研究。在评估的众多社会经济和症状变量方面,85例试验患者与全部符合条件的患者没有差异。治疗退出率为11%。在社会经济或疾病变量方面,接受治疗的患者与退出治疗的患者没有差异。结果表明,至少用本研究中使用的方法无法早期识别退出治疗者。

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