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利用来自鸡蛋黄的特异性免疫球蛋白对犊牛进行牛轮状病毒的被动保护。

Passive protection against bovine rotavirus in calves by specific immunoglobulins from chicken egg yolk.

作者信息

Kuroki M, Ohta M, Ikemori Y, Peralta R C, Yokoyama H, Kodama Y

机构信息

Immunology Research Institute in Gifu, Sano, Japan.

出版信息

Arch Virol. 1994;138(1-2):143-8. doi: 10.1007/BF01310045.

DOI:10.1007/BF01310045
PMID:7980004
Abstract

The efficacy of chicken egg yolk immunoglobulins (yIg) from hens immunized with bovine rotavirus (BRV) serotype G6 (strain Shimane) or serotype G10 (strain KK-3) for protection against homologous BRV in calves was investigated. A significant protection by anti-BRV yIg having 6400 neutralizing antibody titer per dose could be achieved in calves (P < 0.01).

摘要

研究了用牛轮状病毒(BRV)G6血清型(岛根株)或G10血清型(KK - 3株)免疫母鸡所获得的鸡蛋黄免疫球蛋白(yIg)对犊牛抵抗同源BRV的保护效果。每剂具有6400中和抗体效价的抗BRV yIg可使犊牛获得显著的保护作用(P < 0.01)。

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本文引用的文献

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Separation of egg yolk immunoglobulins using an automated liquid chromatography system.使用自动化液相色谱系统分离蛋黄免疫球蛋白。
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Murine rotavirus genes encoding outer capsid proteins VP4 and VP7 are not major determinants of host range restriction and virulence.编码鼠轮状病毒外衣壳蛋白VP4和VP7的基因不是宿主范围限制和毒力的主要决定因素。
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Passive protection against bovine rotavirus-induced diarrhea in murine model by specific immunoglobulins from chicken egg yolk.
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Efficient Production of Human Norovirus-Specific IgY in Egg Yolks by Vaccination of Hens with a Recombinant Vesicular Stomatitis Virus Expressing VP1 Protein.通过用表达 VP1 蛋白的重组水疱性口炎病毒对母鸡进行免疫接种,在蛋黄中高效生产人诺如病毒特异性 IgY。
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Egg yolk IgY antibodies: A therapeutic intervention against group A rotavirus in calves.蛋黄免疫球蛋白Y抗体:一种针对犊牛A组轮状病毒的治疗性干预措施。
Res Vet Sci. 2015 Dec;103:1-10. doi: 10.1016/j.rvsc.2015.09.005. Epub 2015 Sep 8.
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Effect of chicken egg yolk antibodies (IgY) against diarrhea in domesticated animals: a systematic review and meta-analysis.鸡卵黄抗体(IgY)对家畜腹泻的影响:一项系统评价和荟萃分析。
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利用来自鸡蛋黄的特异性免疫球蛋白在小鼠模型中对牛轮状病毒诱导的腹泻进行被动保护。
Vet Microbiol. 1993 Oct;37(1-2):135-46. doi: 10.1016/0378-1135(93)90188-d.
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Relative frequencies of G (VP7) and P (VP4) serotypes determined by polymerase chain reaction assays among Japanese bovine rotaviruses isolated in cell culture.通过聚合酶链反应分析确定的在细胞培养中分离的日本牛轮状病毒中G(VP7)和P(VP4)血清型的相对频率。
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Arch Virol. 1981;69(1):49-60. doi: 10.1007/BF01315265.
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