通过流式细胞术快速测定抗真菌活性。
Rapid determination of antifungal activity by flow cytometry.
作者信息
Green L, Petersen B, Steimel L, Haeber P, Current W
机构信息
Lilly Research Laboratories, Eli Lilly and Co., Indianapolis, Indiana 46202.
出版信息
J Clin Microbiol. 1994 Apr;32(4):1088-91. doi: 10.1128/jcm.32.4.1088-1091.1994.
Abstract
We have developed a rapid assay of antifungal activity which utilizes flow cytometry to detect accumulation of a vital dye in drug-damaged fungal cells. Results of these studies suggest that flow cytometry may provide an improved, rapid method for determining and comparing the antifungal activities of compounds with differing modes of action.
摘要
我们开发了一种抗真菌活性快速检测方法，该方法利用流式细胞术来检测活性染料在药物损伤的真菌细胞中的积累。这些研究结果表明，流式细胞术可能为测定和比较具有不同作用模式的化合物的抗真菌活性提供一种改进的快速方法。
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