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慢性疲劳:4名意大利青少年服用L-色氨酸治疗后嗜酸性粒细胞增多性肌痛综合征的特殊演变

Chronic fatigue: a peculiar evolution of eosinophilia myalgia syndrome following treatment with L-tryptophan in four Italian adolescents.

作者信息

Priori R, Conti F, Luan F L, Arpino C, Valesini G

机构信息

Istituto di Clinica Medica I, Università La Sapienza, Roma, Italy.

出版信息

Eur J Pediatr. 1994 May;153(5):344-6. doi: 10.1007/BF01956416.

DOI:10.1007/BF01956416
PMID:8033924
Abstract

We describe four Italian adolescents in whom a persistent, debilitating fatigue appeared after therapeutic ingestion of products containing L-tryptophan and subsequent to the development of a transient rise in eosinophil count and severe myalgia (Eosinophilia Myalgia Syndrome-EMS). Their clinical picture was indistinguishable from that of the so-called Chronic Fatigue Syndrome. A chronic fatigue may occur after diverse triggering agents and its represents the peculiar clinical evolution of these four paediatric cases of EMS.

摘要

我们描述了四名意大利青少年,他们在治疗性摄入含L-色氨酸的产品后,出现了持续且使人衰弱的疲劳,并且在嗜酸性粒细胞计数短暂升高和严重肌痛(嗜酸性粒细胞增多性肌痛综合征-EMS)出现之后。他们的临床表现与所谓的慢性疲劳综合征无法区分。多种触发因素后可能会出现慢性疲劳,这代表了这四例儿科EMS病例的特殊临床演变。

相似文献

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Chronic fatigue: a peculiar evolution of eosinophilia myalgia syndrome following treatment with L-tryptophan in four Italian adolescents.慢性疲劳:4名意大利青少年服用L-色氨酸治疗后嗜酸性粒细胞增多性肌痛综合征的特殊演变
Eur J Pediatr. 1994 May;153(5):344-6. doi: 10.1007/BF01956416.
2
L-tryptophan-related eosinophilia-myalgia syndrome possibly associated with a chronic B-lymphocytic leukemia.与慢性B淋巴细胞白血病可能相关的L-色氨酸相关嗜酸性粒细胞增多性肌痛综合征
Ann Hematol. 1998 Nov;77(5):235-8. doi: 10.1007/s002770050449.
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Simultaneous development of two cases of eosinophilia-myalgia syndrome with the same lot of L-tryptophan in Japan.在日本,两例嗜酸性粒细胞增多性肌痛综合征同时使用同一批次的L-色氨酸发病。
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J Invest Dermatol. 1993 Jan;100(1):97S-105S. doi: 10.1111/1523-1747.ep12356368.
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[A case of the eosinophilia-myalgia syndrome].[嗜酸性粒细胞增多性肌痛综合征一例]
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引用本文的文献

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Autoantibodies to nuclear envelope antigens in chronic fatigue syndrome.慢性疲劳综合征中针对核膜抗原的自身抗体。
J Clin Invest. 1996 Oct 15;98(8):1888-96. doi: 10.1172/JCI118990.

本文引用的文献

1
L-tryptophan and the eosinophilia-myalgia syndrome: current understanding of the etiology and pathogenesis.L-色氨酸与嗜酸性粒细胞增多性肌痛综合征:病因及发病机制的当前认识
J Invest Dermatol. 1993 Jan;100(1):97S-105S. doi: 10.1111/1523-1747.ep12356368.
2
Chronic fatigue syndrome: a working case definition.慢性疲劳综合征:实用病例定义
Ann Intern Med. 1988 Mar;108(3):387-9. doi: 10.7326/0003-4819-108-3-387.
3
Eosinophilia-myalgia syndrome--New Mexico.嗜酸性粒细胞增多性肌痛综合征——新墨西哥州
MMWR Morb Mortal Wkly Rep. 1989 Nov 17;38(45):765-7.
4
Characterization of "peak E," a novel amino acid associated with eosinophilia-myalgia syndrome.与嗜酸性粒细胞增多性肌痛综合征相关的新型氨基酸“E峰”的特征分析
Science. 1990 Dec 21;250(4988):1707-8. doi: 10.1126/science.2270484.
5
Risk factors associated with chronic fatigue syndrome in a cluster of pediatric cases.一组儿科病例中与慢性疲劳综合征相关的危险因素。
Rev Infect Dis. 1991 Jan-Feb;13 Suppl 1:S32-8. doi: 10.1093/clinids/13.supplement_1.s32.
6
The cause and pathogenesis of the eosinophilia-myalgia syndrome.嗜酸性粒细胞增多性肌痛综合征的病因及发病机制。
Ann Intern Med. 1992 Jan 15;116(2):140-7. doi: 10.7326/0003-4819-116-2-140.
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Natural history of the eosinophilia-myalgia syndrome.嗜酸性粒细胞增多性肌痛综合征的自然病史。
Ann Intern Med. 1991 Sep 15;115(6):437-42. doi: 10.7326/0003-4819-115-6-437.
8
Possible upregulation of hypothalamic 5-hydroxytryptamine receptors in patients with postviral fatigue syndrome.病毒性疲劳综合征患者下丘脑5-羟色胺受体可能上调。
BMJ. 1992 Apr 18;304(6833):1010-2. doi: 10.1136/bmj.304.6833.1010.
9
Psychosocial management of chronic fatigue syndrome in adolescence.青少年慢性疲劳综合征的心理社会管理
Aust N Z J Psychiatry. 1992 Mar;26(1):64-72. doi: 10.3109/00048679209068310.
10
Antinuclear autoantibodies in women with silicone breast implants.患有硅胶乳房植入物的女性体内的抗核自身抗体。
Lancet. 1992 Nov 28;340(8831):1304-7. doi: 10.1016/0140-6736(92)92491-w.