Wells A J
J Am Coll Cardiol. 1994 Aug;24(2):546-54. doi: 10.1016/0735-1097(94)90315-8.
The effects of passive smoking on ischemic heart disease are reviewed. Short-term exposures of 20 min to 8 h result in increased platelet sensitivity and decreased ability of the heart to receive and process oxygen. Longer term exposure results in plaque buildup and adverse effects on blood cholesterol. The available epidemiology is reviewed, and it is concluded that passive smoking increases the coronary death rate among U.S. never smokers by 20% to 70%. The newest Environmental Protection Agency procedures for estimating deaths from passive smoking, when applied to the epidemiologic results on heart disease and passive smoking, indicate that in 1985 an estimated 62,000 ischemic heart disease deaths in the United States were associated with exposure to environmental tobacco smoke. Clinicians are advised to counsel their patients to avoid tobacco smoke at home, at work and in transportation settings.
本文综述了被动吸烟对缺血性心脏病的影响。短期暴露20分钟至8小时会导致血小板敏感性增加，心脏接收和处理氧气的能力下降。长期暴露会导致斑块形成并对血液胆固醇产生不利影响。本文回顾了现有的流行病学研究，并得出结论：被动吸烟使美国从不吸烟者的冠心病死亡率增加了20%至70%。美国环境保护局用于估计被动吸烟导致死亡人数的最新程序，应用于心脏病与被动吸烟的流行病学结果时表明，1985年美国估计有62,000例缺血性心脏病死亡与接触环境烟草烟雾有关。建议临床医生告知患者在家中、工作场所和交通环境中避免接触烟草烟雾。
