Yamamoto T, Albert M J, Sack R B
Department of Bacteriology, School of Medicine, Juntendo University, Tokyo, Japan.
FEMS Microbiol Lett. 1994 Jun 1;119(1-2):229-35. doi: 10.1111/j.1574-6968.1994.tb06893.x.
Capsulated cells of V. cholerae O139 adhered to formalin-fixed or native mucosa of the small intestines from an adult and a child. The primary adherence target was mucus. Capsulated O139 cells adhered better to the antigen sampling cells (M cells) of ileal Peyer's patch than to the absorptive cells. O139 cells on the mucosa appeared as small aggregates. Similar organisms were found on the mucosa of duodenal biopsy samples from patients infected with V. cholerae O139. The findings indicated that capsulated cells of V. cholerae O139 tend to autoagglutinate and contribute to the effective adherence to the intestinal mucosa.
霍乱弧菌O139的荚膜化细胞粘附于成人和儿童福尔马林固定或天然的小肠黏膜。主要粘附靶点是黏液。荚膜化的O139细胞对回肠派尔集合淋巴结的抗原采样细胞（M细胞）的粘附性比对吸收细胞的粘附性更好。黏膜上的O139细胞呈小聚集体形式出现。在感染了霍乱弧菌O139的患者十二指肠活检样本的黏膜上也发现了类似的微生物。这些发现表明，霍乱弧菌O139的荚膜化细胞易于自凝集，并有助于有效粘附于肠黏膜。
