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小鼠的呼吸道病毒感染引发持久的体液免疫反应。

Respiratory virus infection of mice provokes a permanent humoral immune response.

作者信息

Hyland L, Sangster M, Sealy R, Coleclough C

机构信息

Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee 38101.

出版信息

J Virol. 1994 Sep;68(9):6083-6. doi: 10.1128/JVI.68.9.6083-6086.1994.

DOI:10.1128/JVI.68.9.6083-6086.1994
PMID:8057487
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC237018/
Abstract

We have observed that respiratory virus infection of mice provokes an extremely persistent humoral immune reaction, due to a long-sustained population of antibody-secreting cells in the bone marrow. Theories of humoral immunity that strongly distinguish primary and secondary reactions thus may not adequately describe the immune response to respiratory viruses.

摘要

我们观察到，小鼠的呼吸道病毒感染会引发极其持久的体液免疫反应，这是由于骨髓中存在长期持续的抗体分泌细胞群体。因此，强烈区分初次反应和二次反应的体液免疫理论可能无法充分描述对呼吸道病毒的免疫反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f92/237018/2bbb328385f0/jvirol00018-0763-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f92/237018/2bbb328385f0/jvirol00018-0763-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f92/237018/2bbb328385f0/jvirol00018-0763-a.jpg

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