Tranquilli A L, Lucino E, Garzetti G G, Romanini C
Department of Obstetrics and Gynecology, University of Ancona, Italy.
Gynecol Endocrinol. 1994 Mar;8(1):55-8. doi: 10.3109/09513599409028459.
Qualitative and quantitative differences in the dietary habits of postmenopausal women were studied to assess their influence on bone health and osteoporosis. A total of 194 postmenopausal women were studied with forearm DEXA densitometry. 70 were osteoporotic and 124 served as controls. Women had been menopausal for 5-7 years, and had never been treated with hormone replacement or drug therapy. A 3-day dietary recall was completed on Sunday, Monday and Tuesday after the examination: the results were processed by computer and daily calcium, phosphorus and magnesium intakes were related to bone mineral content (BMC). Data were compared with Student's t-test and significance was assessed at p < 0.05. Regression analysis was performed to correlate BMC and intake levels. The dietary intake of calcium, phosphorus and magnesium was significantly reduced in osteoporotic women and correlated with BMC. Calcium and magnesium intakes were lower than the recommended daily allowance even in normal women. The results suggest that nutritional factors are relevant to bone health in postmenopausal women, and dietary supplementation may be indicated for the prophylaxis of osteoporosis. Adequate nutritional recommendations and supplements should be given before the menopause, and dietary evaluation should be mandatory in treating postmenopausal osteoporosis.
研究绝经后女性饮食习惯的质和量的差异，以评估其对骨骼健康和骨质疏松症的影响。对194名绝经后女性进行了前臂双能X线吸收法骨密度测定研究。其中70人为骨质疏松症患者，124人作为对照。这些女性绝经5至7年，从未接受过激素替代或药物治疗。在检查后的周日、周一和周二完成了为期3天的饮食回顾：结果经计算机处理，每日钙、磷和镁摄入量与骨矿物质含量（BMC）相关。数据采用学生t检验进行比较，显著性评估为p < 0.05。进行回归分析以关联BMC和摄入量水平。骨质疏松症女性的钙、磷和镁饮食摄入量显著降低，且与BMC相关。即使在正常女性中，钙和镁的摄入量也低于推荐的每日摄入量。结果表明，营养因素与绝经后女性的骨骼健康相关，饮食补充可能有助于预防骨质疏松症。在绝经前应给予适当的营养建议和补充剂，治疗绝经后骨质疏松症时应进行饮食评估。
