Tn924，一种存在于粪肠球菌染色体上的转座子，其编码对庆大霉素的高水平耐药性。
Tn924, a chromosome-borne transposon encoding high-level gentamicin resistance in Enterococcus faecalis.
作者信息
Thal L A, Chow J W, Clewell D B, Zervos M J
机构信息
Department of Medicine, William Beaumont Hospital, Royal Oak, MI 48073.
出版信息
Antimicrob Agents Chemother. 1994 May;38(5):1152-6. doi: 10.1128/AAC.38.5.1152.
Enterococcus faecalis SF350 is a clinical isolate from Winnipeg, Canada, with high-level (MIC > 2,000 micrograms/ml) gentamicin resistance. The genetic determinant for gentamicin resistance was located on the chromosome of SF350 and could be mobilized by a coresident conjugative plasmid, pYN120. Genetic and physical analyses showed that the gentamicin resistance determinant was located on a 27-kb transposable element which was designated Tn924.
粪肠球菌SF350是一株从加拿大温尼伯分离得到的临床菌株，对庆大霉素具有高水平（最低抑菌浓度>2000微克/毫升）耐药性。庆大霉素耐药的遗传决定因子位于SF350的染色体上，并且可被共存的接合质粒pYN120转移。遗传和物理分析表明，庆大霉素耐药决定因子位于一个27kb的转座元件上，该元件被命名为Tn924。
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