Husstedt W, Steffen U
MMW Munch Med Wochenschr. 1975 May 30;117(22):951-4.
In 53 patients, 24 healthy pregnant women and 29 patients with EPH (edema, proteinuria, hypertension) syndrome, the intravenous phenolsulphonphthalein test was performed between the 32nd and 42 weeks of pregnancy. At the same time, the serum creatinine and estrogen excretion in the 24 hour urine were determined. According to this, normal pregnancy and also pregnancies with one or more symptoms of the EPH syndrome without raised blood pressure do not cause changes of the PSP plasma level. A statistically significant rise in the PSP plasma level is only found with a blood pressure of 140/90 mm Hg, and simultaneously a close correlation to the estrogen excretion in the urine (r = -0.4) and the blood pressure (r = 0.6). Estrogen excretion is reduced with increasing blood pressure (r = -0.75). No correlation could be established between the PSP serum level and the creatinine in the serum.
对53例患者进行了研究，其中包括24名健康孕妇和29例患有EPH（水肿、蛋白尿、高血压）综合征的患者，在妊娠32至42周期间进行了静脉注射酚红试验。同时，测定了血清肌酐和24小时尿中雌激素排泄量。据此，正常妊娠以及患有EPH综合征一种或多种症状但血压未升高的妊娠不会引起酚红血浆水平的变化。仅在血压为140/90 mmHg时发现酚红血浆水平有统计学意义的升高，同时与尿中雌激素排泄量（r = -0.4）和血压（r = 0.6）密切相关。随着血压升高，雌激素排泄量减少（r = -0.75）。酚红血清水平与血清肌酐之间未发现相关性。
