Neufeld M Y, Sadeh M, Cohn D F, Korczyn A D
Department of Neurology, Tel-Aviv Sourasky Medical Center, Israel.
Seizure. 1994 Jun;3(2):135-9. doi: 10.1016/s1059-1311(05)80204-3.
Stress is commonly believed to precipitate seizures in some patients with epilepsy, but direct examination of this assumption is problematic because of the difficulty in defining vague factors such as 'emotional stress'. Using a questionnaire, we have recorded seizure frequency during the 1991 Persian Gulf war, when Israelis were under stress from the threat of Scud missile attacks, in 100 consecutive adult patients with epilepsy. Increased frequency of seizures was reported by eight patients. These were younger than the other patients, the majority showed generalized epileptic EEG activity and all had generalized seizures (secondarily generalized in four). Only four had seizures directly related to the sounding of an alarm and in the others, non-compliance, being off medication at the time and disturbed sleep were probable contributory factors. We conclude that, in this series, epilepsy control was only weakly affected by an acute external emotional stress factor.
人们普遍认为，压力会促使一些癫痫患者发作，但由于难以界定“情绪压力”等模糊因素，直接验证这一假设存在问题。我们通过问卷调查记录了1991年海湾战争期间100例成年癫痫患者的癫痫发作频率，当时以色列人因遭受飞毛腿导弹袭击的威胁而处于压力之下。有8名患者报告癫痫发作频率增加。这些患者比其他患者年轻，大多数表现为全身性癫痫脑电图活动，且均有全身性发作（4例为继发性全身性发作）。只有4例患者的发作与警报声直接相关，而其他患者中，不遵医嘱、当时未服药以及睡眠紊乱可能是促成因素。我们得出结论，在这个系列中，急性外部情绪压力因素对癫痫控制的影响很小。
