妊娠早期羊水、胚外体腔液和母血中维生素A和维生素E的浓度。
Concentrations of vitamins A and E in amniotic fluid, extraembryonic coelomic fluid, and maternal serum in the first trimester of pregnancy.
作者信息
Campbell J, Wathen N C, Merryweather I, Abbott R, Muller D, Chard T
机构信息
Combined Department of Obstetrics, Gynaecology, and Reproductive Physiology, St Bartholomew's Hospital, London.
出版信息
Arch Dis Child Fetal Neonatal Ed. 1994 Jul;71(1):F49-50. doi: 10.1136/fn.71.1.f49.
Paired samples of amniotic fluid and coelomic fluid were obtained by transvaginal ultrasound guided amniocentesis from 15 women with an ultrasonographically normal pregnancy between 8 and 12 weeks' gestation. Vitamins A and E were measured in the two pregnancy fluids and in maternal serum by high performance liquid chromatography with detection by ultraviolet absorption and fluorimetry respectively. Concentrations of vitamins A and E were higher in maternal serum than in coelomic fluid and were generally undetectable in amniotic fluid. All differences in concentration were significant. The vitamin E/cholesterol ratio was similar in maternal serum and coelomic fluid. No correlation was shown between the vitamin concentrations in the three fluids. These findings suggest that the coelomic cavity plays a part in the maternofetal exchange of these vitamins.
通过经阴道超声引导羊膜穿刺术，从15名妊娠8至12周且超声检查正常的孕妇中获取羊水和体腔液的配对样本。分别采用高效液相色谱法，通过紫外吸收检测法和荧光检测法测定两种妊娠液及母体血清中的维生素A和维生素E。母体血清中维生素A和E的浓度高于体腔液，羊水通常检测不到。所有浓度差异均具有统计学意义。母体血清和体腔液中维生素E/胆固醇比值相似。三种液体中维生素浓度之间未显示出相关性。这些发现表明体腔在这些维生素的母胎交换中起作用。
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