Bailly S, di Giovine F S, Duff G W
University Department of Medicine, Royal Hallamshire Hospital, Sheffield, UK.
Hum Genet. 1993 Mar;91(1):85-6. doi: 10.1007/BF00230231.
Analysis of polymerase chain reaction amplified products from the sixth intron of the human interleukin-1 alpha gene reveals a high polymorphism (polymorphism information content = 0.51) in a Caucasian population. Altogether, seven alleles have been defined ranging from 620 to 1220bp. This polymorphism is probably attributable to a variable number of 46-bp tandem repeats, each containing potential regulatory sequences.
对人白细胞介素-1α基因第六内含子的聚合酶链反应扩增产物进行分析，结果显示在高加索人群中存在高度多态性（多态性信息含量=0.51）。总共确定了7个等位基因，长度在620至1220bp之间。这种多态性可能归因于可变数量的46bp串联重复序列，每个重复序列都包含潜在的调控序列。
