Hollander A, Heederik D, Kauffman H
Department of Epidemiology and Public Health, Wageningen Agricultural University, The Netherlands.
Occup Environ Med. 1994 Feb;51(2):73-8. doi: 10.1136/oem.51.2.73.
The relation between bioaerosol exposure in the potato starch industry and work related respiratory symptoms is described. One group of workers was exposed to high dust concentrations (geometric mean up to 56.0 mg/m3) with low endotoxin and antigen concentrations (geometric mean up to 12.6 ng/m3 and 90 relative antigen units (RAU) per m3). A second group was exposed to low dust concentrations (geometric mean up to 3.9 mg/m3), but the endotoxin and antigen concentrations were high (geometric means of environmental samples up to 72 ng/m3 and 2.9.10(2)RAU/m3). Twenty of the 48 workers had specific IgG4 titres to dust extract. Of these 20 workers, 14 showed an increase in IgG4 titre during the first month of the potato processing season. No specific IgE antibodies to dust extracts were found. Twenty two workers were equipped with a Mini-Wright peak flow meter during a four week period. Two workers showed a work related decline in peak flow values. It was concluded that exposure to dust made airborne during the refining process of potato starch may cause work related respiratory symptoms.
本文描述了马铃薯淀粉行业生物气溶胶暴露与工作相关呼吸道症状之间的关系。一组工人暴露于高粉尘浓度（几何平均值高达56.0毫克/立方米），内毒素和抗原浓度较低（几何平均值分别高达12.6纳克/立方米和每立方米90相对抗原单位（RAU））。另一组工人暴露于低粉尘浓度（几何平均值高达3.9毫克/立方米），但内毒素和抗原浓度较高（环境样本的几何平均值分别高达72纳克/立方米和2.9×10²RAU/立方米）。48名工人中有20人对粉尘提取物有特异性IgG4滴度。在这20名工人中，有14人在马铃薯加工季节的第一个月内IgG4滴度有所增加。未发现针对粉尘提取物的特异性IgE抗体。22名工人在四周时间内配备了Mini-Wright峰值流量计。两名工人的峰值流量值出现了与工作相关的下降。研究得出结论，在马铃薯淀粉精炼过程中暴露于空气中的粉尘可能会导致与工作相关的呼吸道症状。
